Background: Hypertensive disorders in pregnancy are one of the major causes of maternal morbidity and mortality. Hypertensive disorders in pregnancy account for 14% of all maternal deaths. An ideal predictor of the disease, the application of which could significantly alter the associated morbidity and mortality, remains elusive. Aim and objective: To study whether raised maternal serum beta hCG in second trimester is associated with increased incidence of Preeclampsia Methodology: 450 antenatal women carrying singleton pregnancy, fulfilling all inclusion and exclusion criteria were included in our prospective observational study. One venous sample were collected from each patient for beta hCG between 12-20 weeks. Patients followed up upto delivery. Outcome measured as development of preeclampsia during pregnancy. All relevant patient data and investigations were analysed statistically using Statistical version 16 [SPSS]. Results and discussion: The incidence of Preeclampsia was 26.88% in our study. In our study among 450 women, 121 developed PE with cut-off value of beta hCG value >82500 mIU/ml. The cut-off value for overall PE group and for mild preeclampsia group are same as 82500mIU/ml. Key Word: serum beta-HCG.
Background: In case of oligohydromnios maternal outcomes are associated with increased intervention in the form of induction of labour and cesarean deliveries due to fetal growth retardation and preterm deliveries indirectly increase maternal morbidity. Fetal outcomes are associated in the form of intrauterine fetal growth retardation, increase risk of meconium aspiration syndrome, low Apgar score, increase NICU admission and congenital anomalies. Method: 50 patients with 37-42 weeks of period of gestation with oligohydromnios confirmed by ultrasonographic measurement of Amniotic fluid index using four quadrant technique. Patients were selected from the opd. Results: In our study incidence of oligohydromnios more found in primigravida (74%). Most common cause of oligohydromnios was idiopathic (30%) followed by pregnancy induced hypertension (25%). Most common cause of cesarean section was fetal distress (32%). Oligohydromnios associated with 40% of Neonatal intensive care unit admission. Conclusion: An amniotic fluid index <5cm. Detected after 37 weeks of gestation is an indicator of poor perinatal outcomes and it increases the risk of cesarean section, so if it detected earlier we can overcome the problem by proper antenatal checkup, councelling and treatment.
Background: Cervical cancer ranks as the second most common cancer among women in India. Incidence is 6-29% approximately of all cancer in India. Objective: The objective of this study is to compare the Sensitivity, Specificity, Positive Predictive Value, Negative Predictive Value and Accuracy of VIA and Pap smear. Method: This was a comparative study done between May 2019 to April 2020. Patients screened from the Gynaecological OPD from the department of Obstetrics and Gynaecology, GMC Ambikapur, Chhattisgarh. Firstly Pap smear was taken followed by VIA was performed with 3-5% acetic acid. Pap smear positive patients are called back for biopsy. Results: In this study total 200 patients have participated, VIA positive in 35 patients(17.5%) and Pap smear positive in 17 patients(3.5%).Out of 17 patients, five were positive for carcinoma cervix(2.5%), seven cases of ASCUS(3.5%), two cases of LSIL(1%), three cases of HSIL(1.5%), patients with NILM were 98(49%).
Conclusion:This study shown that VIA is more sensitive than Pap smear. VIA is easy, low cost and treatment can be administered in the same sitting. By this study we recommended that VIA can be used to screen for cervical cancer in rural areas where Pap smear is difficult and expensive.
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