The present study extended our understanding of the primary structure of isoforms of Cyn d 1.

This study explored the relationship between intimate partner violence (IPV) and current contraception use among ever-married women in Jordan. Analysing a sample (n = 3434) from the 2007 Jordan demographic and health survey, women who reported ever experiencing severe physical violence from their husband were significantly less likely to use contraception than women who did not report severe physical violence (OR = 0.34). Conversely, women who reported ever experiencing sexual IPV were significantly more likely to use contraception (OR = 1.50). Emotional and less severe physical IPV were not significantly related to contraception use. Education, wealth, age, number of children, and fertility preferences were positively associated with contraception use, while residence in the Badia area and consanguineous marriages were negatively associated with contraception use. The findings have implications for the provision of IPV screening and contraception services in Jordan, as well as the specification of services for women most vulnerable to IPV. RÉSUMÉ La présente étude a évalué la relation entre la violence exercée par un partenaire intime et l'utilisation courante de la contraception chez des femmes mariées ou l'ayant déjà été en Jordanie. D'après l'analyse d'un échantillon (n = 3434) de l'Enquête démographique et de santé menée en Jordanie en 2007, les femmes déclarant avoir déjà subi une forme de violence physique grave exercée par leur mari avaient nettement moins tendance à avoir recours à la contraception que les femmes exemptes de violence physique grave (O.R. = 0,34). En revanche, les femmes ayant déclaré avoir déjà souffert de violence sexuelle de la part de leur partenaire intime étaient significativement plus susceptibles d'utiliser un mode de contraception (O.R. = 1,50). La violence psychologique ainsi que la violence physique de gravité moindre exercées par un partenaire intime n'étaient pas significativement liées au recours à la contraception. Le niveau d'études, le revenu, l'âge, le nombre d'enfants et les préférences en matière de fécondité étaient des éléments positivement associés à l'utilisation de la contraception, alors qu'une résidence dans la région de Badia et des mariages consanguins étaient négativement associés au recours à la contraception. Ces résultats ont des conséquences sur l'offre de services de contraception et le dépistage de la violence exercée par le partenaire intime en Jordanie, ainsi que pour le contenu des services destinés aux femmes les plus vulnérables à la violence de leur partenaire intime.‫املتوسط‬ ‫لرشق‬ ‫الصحية‬ ‫املجلة‬ ‫عرش‬ ‫التاسع‬ ‫املجلد‬ ‫العارش‬ ‫العدد‬ 877

The crystal structure of azurin mutant Phe114Ala from Pseudomonas aeruginosa has been solved by molecular replacement. The final crystallographic R value is 0.185 for 9832 reflections to a resolution of 2.6A. The root-mean-square deviation for main-chain atom positions is 0.020 A between the four independent monomers in the asymmetric unit. The mutant Ala114 crystallized from PEG 4000 in a new crystal form and the crystals are monoclinic, P21, a = 51.0, b = 83.6, c = 66.4A and fl = 110.5 ° . The four molecules in the asymmetric unit are packed as a dimer of dimers and are related by an approximate twofold axis. The dimer packing and the dimer contact region are very similar to that of the Alcaligenes denitrificans azurin dimer. The

Cytokeratin-19 is an intermediate filament protein associated with the integrity of cell structure, and its elevated expression has been reported to correlate with the disease progression of oesophagus and lung cancers. In this study, we examined the level of cytokeratin-19 in five cervical cancer cell lines by immunobinding and Western blotting analyses. Compared with two control cell lines, FS-4 (foreskin cell line) and G9T (glioma cell line), all five cervical carcinoma cell lines (Caski, CC7T, ME180, HeLa and SIHA) showed higher cytokeratin-19 expression. By double-staining flow cytometry, expression of cytokeratin-19 in cervical cancer cells was suggested to be in a cell cycle-independent manner. Furthermore, we could specifically localize the SIHA cell-derived tumours in nude mice by injecting with cytokeratin-19-recognized radiolabelled MAb Cx-99 antibody, suggesting the possibility of using cytokeratin-19 as a marker of cervical carcinoma. A clinical investigation was therefore performed on 19 patients (11 patients with cervical carcinoma and eight patients with benign neoplasia). In the 11 patients having cervical carcinoma, all eight patients with advanced stages and one out of three patients with early stage diseases showed higher cytokeratin-19 protein contents than the other 10 patients with benign neoplasia. This suggested that elevation of cytokeratin-19 level was associated with cervical cancer staging. In addition, we have studied the biological significance of elevated cytokeratin-19 level in malignant cervical cancer. The apoptotic rate of cervical carcinoma cells in response to cisplatin was increased if their cellular cytokeratin-19 level was reduced by specific antibody MAb Cx-99. These results indicated that elevation of cytokeratin-19 expression could associate with the apoptotic resistance and malignant progression of cervical carcinoma.