No abstract

Patient scheduling is a difficult task involving stochastic factors, such as the unknown arrival times of patients. Similarly, the scheduling of radiotherapy for cancer treatments needs to handle patients with different urgency levels when allocating resources. High-priority patients may arrive at any time, and there must be resources available to accommodate them. A common solution is to reserve a flat percentage of treatment capacity for emergency patients. However, this solution can result in overdue treatments for urgent patients, a failure to fully exploit treatment capacity, and delayed treatments for low-priority patients. This problem is especially severe in large and crowded hospitals. In this paper, we propose a prediction-based approach for online dynamic radiotherapy scheduling that dynamically adapts the present scheduling decision based on each incoming patient and the current allocation of resources. Our approach is based on a regression model trained to recognize the links between patients’ arrival patterns and their ideal waiting time in optimal off-line solutions when all future arrivals are known in advance. When our prediction-based approach is compared with flat-reservation policies, it does a better job of preventing overdue treatments for emergency patients and also maintains comparable waiting times for the other patients. We also demonstrate how our proposed approach supports explainability and interpretability in scheduling decisions using Shapley additive explanation values. History: Accepted by Erwin Pesch, Area Editor for Heuristic Search & Approximation Algorithms. Funding: Mitacs Accélération IT26995 and Canada Research Chair in Analytics and Logistics in Healthcare (HANALOG). Supplemental Material: The software that supports the findings of this study is available within the paper and its Supplemental Information ( https://pubsonline.informs.org/doi/suppl/10.1287/ijoc.2023.1289 ) as well as from the IJOC GitHub software repository ( https://github.com/INFORMSJoC/2021.0342 ) at ( http://dx.doi.org/10.5281/zenodo.7579533 ).