This study aims to see whether there is an effect of ozone therapy on the wound healing phase of diabetic ulcers in patients with diabetes mellitus at Al Huda Woundcare Clinic Lhokseumawe City in 2016. This research is quassy experiment with samples in this study amounted to 20 patients diabetes mellitus at Al Huda Woundcare Clinic Lhokseumawe City. This research was conducted from 04 until 18 October 2016. Sampling by total sampling method. The analysis used paired t-test (dependent). The result of this research is the age of patient of diabetes mellitus patient at Al Huda Woundcare Clinic of Lhokseumawe city most of the aged between 56-65 years as many as 12 respondents (60,0%) and gender of patient of diabetes mellitus mostly female are 11 respondent (55,0%). The result of paired t test is obtained p-value 0.000 <α = 0,05. This shows that there is influence of ozone therapy to phase wound healing diabetic ulcer in patient of diabetes mellitus at Al Huda Woundcare Clinic of Lhokseumawe City 2016. The results of this study can provide benefits for the community, especially reponden that as an input that ozone therapy can serve as a new treatment alternative in addressing the problems of diabetic wounds with modern wound care so convincing to the public that diabetic wounds can be cured.

Diabetes, where there are blackened wounds from the layers of the skin to the dermis layer and tissue death occurs. The aim of the study was to obtain an overview of the factors that influence the occurrence of wounds in type 2 diabetes patients Gangrene wound or, this wound is a complication caused by someone who has at the Bireuen. The number of respondents in this research amounted to 50 people. Diabetic sufferers who experience injuries, carried out on March 20 to March 25, 2021 with a sampling technique that is accidental sampling. This study shows a risk factor for age 40 years with an OR value of 15.190 and a P-value of 0.000, a risk factor for long suffering from DM ≥ 8 years with an OR value of 8.486 and p = 0.003, a risk factor for a history of diabetic ulcers with an OR value of 9.667. and p = 0.004, the risk factor for lack of foot care with an OR value = 4.500 and p = 0.042, a smoking risk factor with an OR value = 0.371 and p = 0.334, an exercise history factor with an OR value = 8.486 and p = 0.003, family support factor with OR = 1.781 and p = 0.501 which means the variable age 40 years, duration of suffering from DM 8 years. The results of this study can provide information to nurses so as to reduce the incidence of injuries in diabetic patients.