BackgroundThe present study aimed to evaluate the effects of fermented oligosaccharide, disaccharide, monosaccharide and polyols (FODMAP) diet therapy and probiotics on irritable bowel syndrome (IBS) symptoms, quality of life and depression in women diagnosed with IBS.MethodsFor the study, 52 female IBS patients between the ages of 20 and 55 were enrolled. Individuals were monitored for 6 weeks in two groups. A low‐FODMAP diet was given to the first group and a low‐FODMAP diet plus a probiotic supplement was given to the second group (Lactobacillus rhamnosus). Three‐day food intake records were kept at the start of the study and continued up to its conclusion, with a weekly check‐in in between. At the start and end of the trial, participants completed the Hospital Anxiety and Depression Scale, IBS Quality of Life Scale (IBS‐QOL) and IBS Symptom Severity Score (IBS‐SSS). The Bristol Stool Scale was also used by the subjects to record their daily stool densities.ResultsAt the end of the study, it was determined that the daily intake of FODMAP (lactose [g] + oligosaccharides [g] + mannitol [g] + sorbitol [g]) decreased significantly in both groups (p < 0.05). At the end of the study, it was determined that the IBS‐SSS, anxiety and depression scores of the individuals in both groups decreased significantly and their IBS‐QOL scores increased significantly (p < 0.05). However, the difference between these values between the groups was not statistically significant (p > 0.05).ConclusionsA low‐FODMAP diet has been demonstrated to benefit people by lessening the severity of their IBS symptoms and enhancing their quality of life. No evidence was found, however, to indicate that the FODMAP diet would be more beneficial on these metrics if additional probiotics were used. It should be emphasised that the reaction of probiotic strains may vary depending on the IBS subtype.
Amaç: İrritabl bağırsak sendromu olan kadınlarda düşük FODMAP diyet tedavisinin (fermente oligosakkarit, disakkarit, monosakkarit ve polioller) İBS semptomlarına ve yaşam kalitesi üzerine etkilerinin değerlendirilmesidir. Bireyler ve Yöntem: Çalışma, 26 kadın İBS hastası (20-49 yaş) üzerinde yürütülmüştür. Bireyler 6 hafta boyunca düşük FODMAP diyeti uygulamıştır. Çalışma başlangıcında üç günlük besin tüketim kaydı alınmış ve çalışma sonuna kadar her hafta üçer günlük besin tüketim kaydı (her birey için 21 gün) alınarak takip edilmiştir. Bireylere İBS Semptom Şiddet Skoru (İBS-SSS), İBS Yaşam Kalitesi Ölçeği (İBS-YK) ve Hastane Anksiyete ve Depresyon Skalası (HADS) uygulanmıştır. Bulgular: Bireylerin ortalama yaşı 33.1±8.8 yıldır. Günlük FODMAP (laktoz, oligosakkaritler, mannitol ve sorbitol) alım miktarı müdahale sonrasında anlamlı olarak azalmıştır (müdahale öncesi: 13.7±7.98 g, çalışma sonu: 6.7±2.56 g; p<0.05). Çalışma başlangıcında İBS-SSS, HADS anksiyete ve depresyon skoru ve İBS-YK puanlarının sırasıyla medyan değerlerinin 341 [182-475], 12 [3-19] ve 9.5 [0-18] ve 49.3 [5.9-87.5] olduğu, çalışma sonunda ise bu değerlerin sırasıyla 120 [0-375], 9 [0-16] ve 6 [1-13] ile 75.8 [21.3-100] olduğu saptanmıştır. Bu sonuçlara göre bireylerin İBS-SSS ve HADS skorlarının müdahale sonrası anlamlı olarak azaldığı, yaşam kalitesi skorlarının ise anlamlı olarak arttığı görülmüştür (p<0.05). Sonuç: Bu çalışmada düşük FODMAP diyetinin, İBS şiddetinin azaltılmasında ve bireylerin yaşam kalitesinin iyileştirilmesinde olumlu etkileri olduğu saptanmıştır.
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