BackgroundDeep dermal and full‐thickness burns are not only difficult to treat, but they are also associated with significant morbidity and mortality. Recent reports have proposed the use of mesenchymal stromal cells (MSCs) for inducing tissue repair in burn injuries.ObjectiveWe aim to evaluate the effect of allogeneic MSC transplantation on full‐thickness burns with delayed healing.Material and methodsThis study includes five patients with AB B/B burns. All patients received conservative treatments, including cleaning, debridement of necrotic tissue, and silver based dressing on the burn wounds. Cryopreserved allogeneic MSCs were thawed and rapidly expanded and used for application in burned patients. MSCs were implanted into preclotted platelet‐rich plasma onto the surface of burn wounds.ResultsAll treated burn wounds showed early granulation tissue and rapid re‐epithelialization after MSC transplantation. Healing took between 1 and 5 months after MSC transplantation. Repair of burn wounds was associated with slight discoloration of the regenerated skin without hypertrophic scarring or contractures.ConclusionOur results provide evidence of healing in deep‐ and full‐thickness burns by allogeneic MSC transplantation. Rapid healing of burn patients, after MSC transplantation, improves their quality of life and reduces the length of hospitalization. Future studies incorporating a larger number of patients may confirm the results obtained in this work.

Cleft lip is one of the most commonly encountered craniofacial deformities. The comprehensive treatment of cleft lip and palate deformities requires thoughtful consideration of the anatomic complexities of the deformity and the delicate balance between intervention and growth. As evidenced by the multiple techniques that have been developed for its repair, a functionally and aesthetically pleasing result is challenging to attain. In this study, we describe a modification of the surgical technique for the repair of complete unilateral cleft lip and palate, through the design of flag-shaped flaps without removing any tissue, as a modification to the rotation and advancement flaps or Millard technique.