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The adsorption of antibiotic tetracycline onto silica particles was investigated. The effects of pH, electrolyte concentration and temperature on the adsorption equilibrium were examined and the data correlated with a dual site adsorption model. Adsorption of tetracycline onto approximately 9% of the adsorption sites was found to be irreversible, whereas the rest exhibited Langmuir behaviour. Increasing pH of the solution had a strong negative effect on the adsorbed amounts. Adsorption decreased also with increasing ionic strength and temperature. The enthalpy and entropy of adsorption were found to be approximately -16 and -25 J/mol, respectively.

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This study compared the effects of the nonacylated and acylated anthocyanin-rich extracts on plasma metabolic profiles of Zucker diabetic fatty rats. The rats were fed with the nonacylated anthocyanin extract from bilberries (NAAB) or the acylated anthocyanin extract from purple potatoes (AAPP) at daily doses of 25 and 50 mg/kg body weight for 8 weeks. 1 H NMR metabolomics was used to study the changes in plasma metabolites. A reduced fasting plasma glucose level was seen in all anthocyanin-fed groups, especially in the groups fed with NAAB. Both NAAB and AAPP decreased the levels of branched-chain amino acids and improved lipid profiles. AAPP increased the glutamine/glutamate ratio and decreased the levels of glycerol and metabolites involved in glycolysis, suggesting improved insulin sensitivity, gluconeogenesis, and glycolysis. AAPP decreased the hepatic TBC1D1 and G6PC messenger RNA level, suggesting regulation of gluconeogenesis and lipogenesis. This study indicated that AAPP and NAAB affected the plasma metabolic profile of diabetic rats differently.

B. (2019). Anthocyanin-rich extract from purple potatoes decreases postprandial glycemic response and affects inflammation markers in healthy men. Food Chemistry.