The objective of this research was to study the effect of replacement of fish meal with maggot meal for growth and survival rate and to determine the best percentage of substitution maggot meal in the diets of nile tilapia (Oreochromis niloticus) growing. Maggot used was the result of mass culture through the rearing of Black Soldier Fly (BSF) in the cage to produce eggs. Furthermore, the eggs harvested and spread on the medium of palm kernel cake for bioconversion process for 10 days and harvested, dried and milled. Replacement of fish meal with maggot meal in diets as a treatment was A (0%), B (10%), C (20%), D (30%), and E (40%) with a feed protein content 30%. The total of 350 nile as test fish with an average weigth 10-12g were cultivated in 15 units of aquarium 60 l and nurtured for 49days. The experimental method used was a completly randomized design and were analyzed by ANOVA and multiple comparisons. Among treatment means were made with Duncan's multiple comparison test using the Statistical Analysis Software Program of SPSS version 21 for Windows. all probability values were considered statistically significant at the level of P< 0.05. The result of this study show that replacement fish meal with maggot meal at various percentages of dietary treatments have a significant effect on growth, survival rate, and FCR, nevertheless the most optimal percentage is at 30%.