Mobile learning technologies have the potential to change higher education teaching, participation and learning now and in the future. This chapter investigates contributing factors and how these are positioned and considered within higher education in Laos PDR and Cambodian universities. It investigates the cases of two university-based agriculture courses. In particular, it explores the issues under consideration by educators as they develop degree programs that enhance flexibility and learning outcomes through the incorporation of mobile technologies. Literacies, access, barriers and participation associated with adopting mobile learning technologies in higher education in these two countries are explored from the perspectives of the student and the lecturer. The chapter considers the functional aspects of mobile learning relevant to participation and learning including dissemination and access to information and communications, enabling person to person connections in education, and connecting and intersecting learning content with the situated contexts of the learner. Access issues and barriers to the use of the technology within programs are considered. Key insights associated with mobile learning adoption within these universities are highlighted at each of pedagogical, technical and organisational levels.