Abstract. Understanding the genetic influence on aggressive behavior in children is one way to understand pathways to the development of aggression in adults. While aggression is likely under some environmental influence, it is also likely under some genetic influence. Overt aggression associates with a variety of genes including dopaminergic and serotonergic genes. Dopaminergic and serotonergic genes are known to be associated with overt aggression. However, little is known regarding the genetic pathways associated with relational aggression. Detecting genetic associates of relational aggression is important to eventually understand pathways to socially aggressive behaviors in children. Therefore, we attempted to determine if relational aggression was also associated with dopaminergic and serotonergic genes. We invited the parents of 327 children to complete a modified version of the MacArthur Health and Behavior Questionnaire (HBQ-P), which has a subscale for relational aggression. We used logistic regression models that predicted relational aggression after controlling for covariates. One genetic predictor was added at a time until there was no model improvement. The covariates were overt aggression scores obtained from the HBQ-P and age. The final (best) model included as a significant predictor of relational aggression one single nucleotide polymorphisms (SNP) on SLC6A3 (rs2617605) and the covariates.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.