Many households in developing countries routinely use pesticides without any safety considerations. The objective of this study was to determine types of pesticides and pesticide-use practices of the residents, to determine self-reported adverse effects resulting from pesticide use and to assess the impact of educational intervention on pesticide use behavior in the study area. Commercially available pesticide samples were collected from pesticide vendors in the area. Pre -tested questionnaires were distributed to 375 family heads. Data was expressed as frequency and percentages.Educational intervention on safe pesticide use was carried out. Pre and post intervention behavior were compared using paired t test. Relationship between demographic variables and pesticide use practices were explored using Chi Square statistics. A p value of less than 0.05 was considered significant. Prevalent pests were mosquitoes, cockroaches, rats, bedbugs, ants, termites, houseflies, ticks and scorpion. The major constituent of pesticides in this environment was Dichlorvos (DDVP). Many commercially available pesticides were unlabeled. Nearly half, 48.8% had used pesticides in the home. More than three quarters, 78.7% indicated that they read instructions before using pesticides. More than one third, 36% had experienced health problems attributed to pesticide use. Many locally available pesticides were unlabeled. Majority of labelled pesticides contained mainly Diclorvos (DDPV). Unsafe pesticide handling practices were common. The most common self -reported adverse effect was respiratory symptoms. Educational intervention increased in the proportion of respondents that used of non-chemical methods and adopted safer pesticide use practices. Keywords: Pesticides, Diclorvos (DDPV), Educational Intervention, Pharmacist, Nigeria

Abstract   Background Medicines can be potentially dangerous when used wrongly. This work examined drug combinations in pain management among attendants in retail drug outlets in  Obiaruku, Delta State, Nigeria.       Objectives The objective of this study was to describe drug combination in the management of pains by attendants working in community pharmacies and patent medicine shops (PMSs)         Method This was a cross-sectional descriptive study using the ‘’surrogate shopper’’ approach to explore the real day-to-day practices and extract required information in twelve retail drug outlets located in the study area. Conversations were tape recorded and thereafter composition of   single doses of pain relievers   recommended by attendants   were analyzed. Results A total of 12 retail outlets were visited. The average number of pills contained in a single dose pain reliever was 6.80±2.35 (for pharmacy outlets) and 5.33±1.32 (for PMSs), p>0.05. Piroxicam (14, 73.7%)   was   most frequently used NSAID. More than half,   63.2% of the attendants included single tablet of Prednisolone, 5mg in their pain relief combination. Other drugs not indicated for analgesia were included in the single dose combo. This includes Vitamin B complex (2, 10.5%), cod liver oil,   Sulfadoxine – pyrimetamine (1, 5.3%), Salbutamol and Ferrous sulphate (1, 5.3%) and multivitamin (12, 63.2%).There was no   significant difference in pain management practices between Pharmacies and Patent medicine stores (PMSs)   (p>0.05). Conclusion Polypharmacy and irrational use of NSAIDs was   a common practice among shop attendants in retail drug outlets, resulting in avoidable drug therapy problems and posing serious risk to public health.