Optical coherence tomography (OCT) is a modern, non-contact method of diagnostic examination that enables the visualization of various tissues of the human eye in a cross-sectional view at the microscopic level with the required morphological information. The software pre-installed in such devices contains many different tools for analyzing scans and has almost all the functionality necessary for the doctor to make a correct diagnosis. However, as time passes, more and more advanced methods of analyzing the images appear, which actualizes new tasks of developing additional software that can supplement and expand the functionality of the diagnostic equipment. This paper proposes an algorithm for automatic segmentation of the borders of a pathological focus in the macular area of the retina to calculate the area of the pathological focus, which together with other algorithms for analysis of morphometric parameters of the human eye, which are still under development, will be used for more accurate diagnosis of the stage of age-related macular degeneration.

Aim of the research. Study of clinical efficacy of treatment of wet form of age-related macular degeneration by using the method of introduction of the inhibitor of angiogenesis into the back s ubtenon s pace on the viscous media. Material and methods of the study. The first group (main group) included 41 patients (43 eyes) with wet form of age-related macular degeneration (AMD). All patients in this group were injected in the back subtenon space 7.5-12.5 mg of an angiogenesis inhibitor on a viscous medium (1.0 ml of 2% solution of hydroxypropylmethyl cellulose). The second group (control group) consisted of 30 patients (30 eyes) with wet form of AMD, for this group a retrospective analysis of dynamics of morpho-functional indices after intravitreal injections of angiogenesis inhibitors according to standard methods (1.25 mg) was carried out. The observance time period amounted to 12 months. Results. When comparing the effectiveness of treatment, the mean best-corrected visual acuity (BCVA) improved significantly in both groups after treatment. Also, according to data of the optical coherence tomography (OCT), the mean central retinal thickness (CRT), the extent, height of pathological changes, the area of the pathological focus and the relative volume of the pathological focus were significantly reduced as a result of treatment. No significant differences were found between the groups (all p>0.05). In accordance with results of the evaluation, the effect duration at subtenon method of administrations amounted to 2-2.5 months, at intravitreal method it amounted to 1-1.5 months. The number of administrations in the 12 months of observation in the main group amounted to 2.8 injections per patient on average, and in the control group it amounted to 4.2 injections. Conclusion: Subtenon injections of the inhibitor of angiogenesis into the back subtenon space gives the positive effect in the treatment of wet form of age-related macular degeneration, and its application on viscous medium has a prolonged effect.