A child presented with excessive bruising and prolonged activated partial thromboplastin time. Mixing studies in plasma were positive for phospholipid dependence of the anticoagulant, confirming a diagnosis of lupus anticoagulant. Factor II level was reduced. Laboratory findings normalised after three months, with spontaneous resolution of bruising. This case demonstrates a transient antiphospholipid antibody syndrome as a rare presentation of bleeding diathesis in a previously healthy child, and should be considered in children with new onset bruising and prolonged activated partial thromboplastin time.

Summary A case of mucocutaneous sporotrichosis presenting as mycotic pansinusitis with polyposis with intracranial and intraorbital extension in a patient from Punjab, India is described. The patient had nasal discharge, sneezing and nasal obstruction for 12 years, had undergone repeated surgeries (for endoscopic clearance) but had recurrence. Computerized tomography (CT) and magnetic resonance imaging (MRI) findings revealed pansinusitis. A definitive diagnosis of sporotrichosis was established by culture of Sporothrix schenckii, verification of its dimorphic character and a positive pathogenicity test. The patient was successfully treated with potassium iodide and itraconazole.

Ear discharge specimens from 182 clinically diagnosed cases of chronic suppurative otitis media were cultured for isolation of fungi and bacteria. Positive fungal cultures were obtained in 13.7 % ; present alone in 7.6% and incombination with various bacteria in 6.1%. Bacteria alone were present in 60.4% cases. The fungal isolates were candida albicans (60%) and Aspergillus (40%). Bacterial isolates showed the predominence of pseudomonas aeriginosa (44.8%) followed by Staphylococcus aureus (20.4%). Newer antibiotics like Cefotaxime, Gentamicin and Ciprofloxacin were found to be more effective against all the gram positive and negative isolates.