Sickle cell anaemia is an excruciating disease with anaemia as a major pathological issues in the patients. Developing worlds are affected heavily by sickle cell anaemia and in malaria endemic region with high prevalent sickle cell trait. IDA and iron deficiency anaemia are common in thyroid disease and can lead to fatigue. Both hypothyroidism and hyperthyroidism can cause iron deficiency and anaemia. In turn, iron deficiency can also trigger hypothyroidism. Iron deficiency/IDA symptoms are similar to those of thyroid disease, making them hard to spot. Healthcare providers can order a blood test to check iron levels. This is called a serum ferritin test. Treatment for iron deficiency includes thyroid replacement medication, iron supplements, and/or a high-iron diet. Vitamins C, B6, B12, and others may improve iron absorption. When you have two conditions with similar symptoms, it can be hard to tell what's causing what symptoms. Pay attention to any new or worsening symptoms. Also, look at what does and doesn't improve with thyroid treatments. If you're still fatigued when your thyroid levels return to normal, talk to your doctor about the possibility of iron deficiency and IDA. Keywords: hyperthyroidism, anaemia, sickle cell, nutritional and anaemia.

Iron-deficiency anemia is the most frequent form of anemia in pregnancy and can have serious consequences for both the mother and fetus. The majority of women do not have adequate iron stores to meet the dramatic increase in requirements during the second and third trimester of pregnancy. However, there is increasing evidence that intravenous iron is more effective, provides more rapid haemoglobin correction, corrects iron stores and is better tolerated than oral iron in treating iron-deficiency anemia during pregnancy. The reported prevalence of anemia in this study is high and routine screening of pregnant women is highly recommended and further studies to explore during pregnancy is a public health problem in developed and developing countries. Pregnant women are at risk of developing anemia due to increased nutrient needs which include iron, folate and Vitamin B12 and haemo-dilution during pregnancy. Keywords: Anemia, heamoglobin, red cells, pregnancy, Africa.

In this study, Lactobacillus salivarius was isolated from human saliva by culture technique using MRS medium, identified through relevant biochemical protocols, and compared to a known control of Lactobacillus acidophilus sourced from Puritan Pride Inc., Qadelade, New York, USA. Primary isolation of microorganisms of interest was carried out at Cheznik Diagnostic and Research laboratories while animal preparation and treatment were carried out at Animal Farm, Mgbakwu Awka. Twenty wistar rats were used as the test animals and another twenty for positive control. The animals in the test group were induced to diarrhea using 1 ml of castor oil following 12-hour fasting while the control group was fed with daily feed and distilled water. The test animals upon production of diarrhoeic stool were fed with 1 × 10 9 cfu/ml (410 mg/dl w/v) of the Lactobacillus sp isolate in distilled water. The diarrhoea was resolved within 24 hours of treatment. The average weights of the animals taken just after preparation and early treatment (T x ) showed appreciable loss in weight among the test animals possibly due to stress compared to initial weight at T 0 . However, upon continued treatment with the isolate, obvious weight gain (Tf) compared to T x was observed. The results of the haematological data at the final analysis showed proximal values and consistency to that of the control group following administration of the Lactobacillus sp isolate. The routine general health data of the test animals showed marked improvement upon treatment with the isolate. A test of significance at 0.05 showed a positive agreement (p < 0.05). The isolated Lactobacillus sp