Open cell Ti6Al4V foams (60% porosity) were prepared at sintering temperatures between 1,200 and 1,350°C using ammonium bicarbonate particles (315-500 lm) as space holder. The resulting cellular structure of the foams showed bimodal pore size distribution, comprising macropores (300-500 lm) and micropores (1-30 lm). Compression tests have shown that increasing sintering temperature increased the elastic modulus, yield and compressive strength, and failure strain of foams. The improvements in the mechanical properties of foams prepared using smaller size Ti64 powder with bimodal particle distribution were attributed to the increased number of sintering necks and contact areas between the particles. Finally, the strength of foams sintered at 1,350°C was found to satisfy the strength requirement for cancellous bone replacement.
The addition of EEP to GIC increased the microhardness of the GIC and did not adversely affect the microleakage. Thus, it might be used during routine dental practice due to its antibacterial properties.
Staphylococcus epidermidis is the primary cause of medical device-related infections due to its adhesion and biofilm forming abilities on biomaterial surfaces. For this reason development of new materials and surfaces to prevent bacterial adhesion is inevitable. In this study, the adhesion of biofilm forming S. epidermidis strain YT-169a on nitrogen (N) ion implanted as well as on as-polished CoCrMo alloy materials were investigated. A medical grade CoCrMo alloy was ion implanted with 60 keV N ions to a high dose of 1.9 Â 10 18 ions/cm 2 at substrate temperatures of 200 and 4008C. The near-surface implanted layer crystal structures, implanted layer thicknesses, and roughnesses were characterized by XRD, SEM and AFM. The number of adherent bacteria on the surfaces of N implanted specimens was found to be 191 Â 10 6 CFU/cm 2 for the 2008C and 70 Â 10 6 CFU/cm 2 for the 4008C specimens compared to the as-polished specimen (3 Â 10 6 CFU/cm 2 ). The adhesion test results showed that S. epidermidis strain YT169a adhere much more efficiently to the N implanted surfaces than to the as-polished CoCrMo alloy surface. This was attributed mainly to the rougher surfaces associated with the N implanted specimens in comparison with the relatively smooth surface of the as-polished specimen.
The effects of alkali and nitric acid surface treatment and acid etching on the CaP deposition of an open cell Ti6Al4V foam (60% porous and 300-500 mm in pore size) developed for biomedical applications were investigated in a simulated body fluid (SBF) solution for 14-day. The surface roughness of the foam specimens ground flat surfaces was measured in nano-metric scale before and after SBF immersion using an atomic force microscope (AFM). A significant increase in the surface roughness of alkali treated foam specimen after SBF immersion indicated a smaller crystal size CaP deposition, which was also confirmed by the AFM micrographs. The microscopic evaluation clearly showed that alkali treatment and nitric acid treatment induced a continuous, uniform CaP deposition on the cell wall surfaces of the foam (interior of cells). While in untreated foam specimen the cells are filled with CaP precipitates and acid etching did not produce a continuous coating layer on particles interior of the cells. The coating layer thickness was $3 mm in alkali treated foam specimens after 14-day of SBF immersion, while nitric acid treatment induced relatively thinner coating layer, 0.6 mm. #
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