ÖZETHoloprozensefali, embriyonel hayatın 35-42. günleri arasında telensefalon ve diensefalona bölünmesi gereken prozensefalonun çeşitli derecelerde yetersiz bölünmesi sonucu oluşan bir tablodur. Hastalık, şiddetine göre alobar, semilobar ve lobar tip olmak üzere üç gruba ayrılır. İzole olabildiği gibi çeşitli sendromlara da eşlik edebilen holoprozensefalinin prognozu, beyin ve fasiyal deformitelerin şiddetine ve ilgili anomalilerin varlığına bağlıdır. Bu çalışmada, 21 haftalık bir gebede şiddetli semilobar holoprozensefali saptanan fetusun, obstetrik ultrasonografi sonrası elde edilen manyetik rezonans görüntüleme bulguları sunulmaktadır.Anahtar Kelimeler: Holoprozensefali, manyetik rezonans görüntüleme, ultrasonografi, semilobar holoprozensefali. ABSTRACTHoloprosencephaly is a clinical condition that results from incomplete division of prosencephalon into telencephalon and diencephalone in different phases between 35-42 days of embryogenic life. The disease can be divided into three grades; alobar, semilobar and lobar based on the degree of severity. The prognosis of holoprosencephaly which could also be an isolated anomaly depends on the severity of the brain and facial deformities and presence of associated anomalies. In the present study, we report the findings magnetic resonance imaging of a fetus with severe semilobar holoprosencephaly in 21st week of gestation first detected by obstetric ultrasonography.

Tuberculosis as an important health problem of our age causing death of 2 million people each year. The incidence of tuberculosis in the pediatric age group is 1.3 millions/year and it is estimated that 450,000 cases result in death. WHO reports that %15-25 of cases are extrapulmonary tuberculosis patients. Here we present a rare case of abdominal tuberculosis who had no immunsupression with isolated bilateral psoas abscesses and inguinal lymph node involvement. (Turk Arch Ped 2011; 46: 331-3)

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