Aim: The aim of this study is to determine the effect of smartphone screen time on general health status of adult patients with cancer compared to healthy participants in a Turkish population amidst the COVID-19 pandemic. Materials and Methods: 146 participants took part in this study, 81 of them were cancer patients. The mean screen time throughout their last week was obtained from the smartphones of all participants. The health status of participants was analyzed via the General Health Survey (GHS) which was a self-reported questionnaire including 12 items rated on a Likert scale. The relationship between screen time and GHS score and related factors for participants was compared. Results: The median screen time and GHS of participants  were 180 minutes (10-945) and 13.5 (4-28), respectively. After screen time was categorized in respect to the mean of 180 minutes, A younger age (p=0.007), higher educational status (p=0.03), and early-stage disease (p=0.03) were each associated with increased screen time. Cancer stage had a correlation with GHS (add p value and correlation coefficient). While educational level was positively related with screen time (r=0.216, p=0.009), age (r=-0.471, p<0.001) and cancer stage (r=-0.332, p=0.03) were negatively correlated. Screen time was not found to be associated with GHS scores in both cancer patients and healthy participants. Conclusion: Although smartphone usage has been increasing secondary to the dependence on social networks and increasing in-person restrictions, it did not affect the mental wellbeing among patients with cancer nor healthy participants.

Metabolic rate of glucose uptake is generally controlled by a feedback mechanism covering islet β cells and insulinsensitive tissues, wherein tissue sensitivity to insulin influences the level of β-cell comeback. In case of insulin presence, β cells preserve standard glucose tolerance via enhancing insulin production. Even though β-cell dysfunction has a strong hereditary component, environmental alterations carry an important part as well. Current research methods have facilitated to establish the important part of hexoses, amino acids, and fatty acids in the development of insulin resistance and β-cell dysfunction, therefore more operative treatments to slow the progressive loss of β-cell function are required. Latest discoveries from clinical research deliver significant information about approaches to stop and treat diabetes and some of the adversative properties of these interferences. Generation of satisfactory numbers of pancreatic endocrine cells that work in the same way as primary islets is of supreme prominence for the expansion of cell treatments to cure. In this study, we focused on different techniques starting from islet and pancreas transplantations individually and ending on new therapies such as stem cell technology and bioengineering. We aimed to establish a comprehensive and detailed explanation of treatment perspectives for islet cell loss. This review is carrying a novel potential for enlightening the current treatments and future-based therapies.