Abstract:The present contribution encompasses on plankton and biological productivity as ecological indicator for identifying the ecological quality of Sahastradhara stream (between 27 km stream stretches), located in the Doon Valley of Garhwal region in India. Monthly sampling from all the sampling sites was made for a period of 12 months (May 2009 -April 2010 at 9:00-11: 00 AM. A total of 40 taxa from different classes of plankton and zooplankton were reported. The phytoplankton (32 sp.) was found being the most abundant taxa than zooplankton (9 sp.) in Sahastradhara stream. Fluctuation in the phytoplankton density was recorded highest (1536 unit/l) during winter and lowest (20 unit/l) during monsoon. Zooplanktons were reported to be maximum (147 unit/l) during summer and minimum (3 unit/l) during monsoon. The total diatoms were reported highest (1022unit/l) during starting the winter and lowest (4 unit/l) during monsoon. Green algae and blue green algae were reported to be maximum during winter and minimum during summer. The Shannon-wiener diversity index calculated for the density of Bacillariophyceae (0.2180-0.366), Chlorophyceae (0.208-0.367) and Cyanophyceae (0.391-0.366) and correlation was made between Plankton biomass and physico-chemical parameters to analyses the relative features of the both variables. The density of plankton and biological productivity were influenced by disturbances in the photic zone and indiscriminate anthropogenic activities for tourist development resulted aquatic habitat degradation in stream ecosystem.

Objective: Protective effect of bee propolis against anti-tuberculosis (TB) drugs (rifampicin and isoniazid)-induced hematological toxicity in Sprague Dawley (SD) rats.Methods: Experimental male SD rats weighing 180±20 g were randomly assigned into eight groups (n=6), the Group 1 served as control; Group 2 received 200 mg bee propolis/kg body weight; Groups 3, 5, and 7 were treated with drugs 100 mg rifampicin/kg body weight, 50 mg isoniazid/kg body weight, and 100 mg rifampicin+50 mg isoniazid/kg body weight, respectively. Groups 4, 6, and 8 were treatment groups receiving 200 mg bee propolis/kg body weight+100 mg rifampicin/kg body weight, 200 mg bee propolis/kg body weight+50 mg isoniazid/kg body weight, and 200 mg bee propolis/kg body weight+100 mg rifampicin+50 mg isoniazid/kg body weight, respectively. All the treatments were given for 30 days, and then, the rats were sacrificed under light esthesia by cervical dislocation and blood was collected for physiological studies.Results: Bee propolis supplementation (200 mg/kg body weight) showed increased level of hemoglobin with respect to rifampicin (15.45%), isoniazid (11.34%), and rifampicin plus isoniazid (5.04%) administered groups after 30 days of treatment. Moreover, the decreased level of red blood cell count and white blood cell count by anti-TB drugs rifampicin, isoniazid, and rifampicin plus isoniazid together was also elevated in treatment group with bee propolis. Conclusion:Coadministration of propolis (200 mg bee propolis/kg body weight) with drugs helped modulate the toxic effects by restoring tested values to near normal.

Objective: The aim of this study is assessment of protective role of bee pollen in antituberculosis drug (rifampicin and isoniazid)-induced toxicity in testis of Sprague Dawley rats.Methods: Healthy rats weighing 180±20 g were selected for the study. Rats were divided into five groups, i.e., Group A (control), Group B (100 mg/kg body weight/day rifampicin-treated), Group C (rifampicin 100 mg/kg body weight and bee pollen 100 mg/kg body weight), Group D (isoniazid 50 mg/kg body/day treated), and Group E (isoniazid 50 mg/kg body weight/day with bee pollen 100 mg/kg body weight/day) serve as experimental groups.Results: Aqueous extract of bee pollen when administered along with the antituberculosis drugs (rifampicin, isoniazid) showed significant reduction in the level of malondialdehyde while the activity of superoxide dismutase, glutathione (GSH) reductase, glutathione peroxidase, glutathioneStransferase, catalase, and GSH was elevated representing the antioxidant potential of bee pollen against the drug-treated groups. Supplementation of bee pollen significantly reduced histological changes in the testis of drug-induced groups such as smaller epithelial height, germ cell loss, and irregular seminiferous tubules to near normal. Conclusion:Bee pollen has shown the modulatory effect against damage and oxidative stress induced by antituberculosis drugs (rifampicin and isoniazid) in rat testis.

Abstract:The present study aims to identify the ground water contamination problem in villages located in the close vicinity of Gajraula industrial area at Gajraula (U.P.), India. Ground water samples were collected from different villages at the depth of 40 and 120 feet from earth's surface layer. Analytical techniques as described in the standard methods for examination of water and waste water were adopted for physico-chemical analysis of ground water samples and the results compared with the standards given by WHO and BIS guidelines for drinking water. Water quality index was calculated for quality standard of ground water for drinking purposes. The present investigation revealed that the water quality is moderately degraded due to high range of seven water quality parameters such as Temperature (18.

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