Background: Our aim was to determine the efficacy and safety of intragastric balloon (IGB) application and the factors affecting its success by evaluating the results of patients who underwent IGB.Materials and Methods: A total of 277 consecutive patients that underwent IGB between January 2019-September 2020 in our clinic were evaluated. Patients' demographic data, height and weight before the IGB procedure, weight at 6 and 12 months after the procedure, follow-up period, complication status, and whether they received dietician's assistance during the follow-up were recorded.Results: In 5 (1.8%) patients, IGB was removed for various reasons before the standard period of 6 months. The mean age of the patients was 35.6 ± 9.5 years, the mean baseline weight and body mass index (BMI) was 92.6 ± 14 kg and 33.5 ± 5.4 kg/m 2 respectively. The mean follow-up time was 13 ± 4.9 months, whereas in 146(53.6%) patients the follow-up was ≥ 12 months. In the 6-month follow-up, the mean %excess weight loss and %body weight loss were 65.65 ± 25.19% and 14.69 ± 6.96%, respectively, whereas at the 12-month follow-up they were 32.38 ± 24.79% and 6.56 ± 5.31%, respectively. High BMI (odds ratio = 1.2, 95% CI = 1.0-1.2) and not receiving dietitian's assistance (odds ratio = 8.5, 95% CI = 3.1-23.7) were independent risk factors for unsuccessful IGB application at both 6-month and 12-month follow-ups. Conclusion:IGB application is a relatively effective and safe weight loss treatment for overweight and obese individuals. High BMI and not getting help from a dietician are risk factors for failure of IGB. To increase compliance with dieticians and therefore success of IGB application, patients should undergo psychiatric evaluation before IGB procedure, and receive psychiatric support, if necessary.