An 18-year-old male with a medical history of trigeminal neuralgia presented to the emergency department with complaints of severe abdominal pain associated with nausea, projectile vomiting, and watery diarrhea with no fever, rigors, and chills. The abdominal examination was unremarkable. His lab results showed elevated serum lipase and amylase. Gallstones were ruled out by abdominal ultrasonography. His computed tomography (CT) revealed pancreatic enlargement with ill-defined borders. He reported cocaine use but had no history of alcohol abuse. A urine drug screen was positive for cocaine. He was managed conservatively with a possible diagnosis of acute pancreatitis due to cocaine abuse after carefully ruling out other causes. The patient was symptom-free on day 7 and discharged from hospital on day 8 with follow-up with his gastroenterology doctor and drug counseling service. Although cocaine-induced pancreatitis is rare, it should be considered a differential diagnosis in patients with a history of cocaine use.
A 51-year-old woman with a past medical history of migraine presented with severe headache for the last three weeks. The pain was intermittent and throbbing in nature. She has not experienced any headaches in the past several years. She took her migraine pills and over-thecounter analgesics, but the pain did not resolve. Initial evaluation including physical exam and neurological exam was normal. Her serum chemistry was unremarkable and CT scan of the brain was nonsignificant. The patient was diagnosed with possible trigeminal neuralgia and the pain resolved after being started on tegral (carbamazepine). Unilateral headache is a typical presentation of atypical trigeminal neuralgia and is rarely reported in literature.
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