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For the past three decades, the Philippines’ expertise in nuclear science and technology (S&T) has diminished resulting from the shutdown of the Philippine Research Reactor-1 (PRR-1) in the 1980s. In addition, the mothballed Bataan Nuclear Power Plant (BNPP) and the low confidence in nuclear technologies led to the non-prioritization of nuclear science in the country. Consequently, new nuclear facilities were never re-introduced, and the transfer of knowledge declined and nuclear applications were limited to radiation and isotopic studies. If the current initiatives of the Philippines in the use of nuclear energy will push through, the country will need competent human resources who will be responsible for building the nuclear facilities and their safe operation. To augment the declined nuclear expertise in the country, the DOST-PNRI implemented capacity building activities to reestablish and sustain knowledge and expertise in nuclear S&T in the country. Activities that were implemented include the development of training materials for undergraduate students and the development of research facility using isotopic neutron sources. This paper discusses the capacity building strategies implemented and their significant outputs, as well as plans for sustainability and continual development.