Background: Diabetic foot ulcers is a major complication of diabetes mellitus, and precedes >80% of all diabetes related lower leg amputations. One of the risk factors in non-healing diabetic ulcer is low serum albumin level. The objectives of this study were to study the effect of low serum albumin level in patients with diabetic foot ulcer and to study the factors affecting wound healing in diabetic ulcer. Methods: Prospective cohort study in a tertiary hospital. Results: The mean age among study was 57.8 out of which 68.3% were males and 31.7% were females. 55% patients presented with slough over ulcer, 29.2% patients presented with healthy granulation and 15.8% patients presented with extensive wound infection. Among study group 50% patients had good glycaemic control and 50% patients had poor glycaemic control. Conclusions: Low serum albumin level is one of the attributable risk factor of non-healing ulcers in diabetic foot. Poor glycaemic status is also a risk factor for non-healing ulcer.
Background: Acute pancreatitis still remains a disease of growing burden to mankind; it is an unpredictable, potentially lethal disease with a high mortality. The incidence of acute Pancreatitis appears to be increasing. Aim of the study was to evaluate total serum calcium and corrected calcium as prognostic severity factors in acute pancreatitis. Methods: This prospective study was conducted in a tertiary hospital from July2015 to June 2016. All the patients who were diagnosed to have acute pancreatitis by clinical examination, laboratory, radiological and biochemical investigations were considered as cases. Serum calcium and albumin corrected calcium measured within 24 hours of admission. Patients followed up for a maximum period of 4 weeks and outcome studied, in terms of whether patient had local or systemic complication, mortality. Significance of serum calcium and albumin corrected calcium in predicting outcome of acute pancreatitis is assessed and compared with BISAP score. Results: Acute pancreatitis most commonly occurs in the age group of 30-50. 80% of acute pancreatitis occurs in male and 20% in female. Alcoholism accounts for 58% cases of acute pancreatitis and gall stone account for 28% of acute pancreatitis. Conclusions: Hypocalcaemia and low ACC can predict severity of acute pancreatitis, as with BISAP score, but it is not superior to BISAP score.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.