Solid pseudopapillary tumor of pancreas is a very rare tumor of low malignant potential accounting for only 2-3% of all pancreatic neoplasms. It affects females of African American ethnicity. The tumor biology is unique in itself. It is seen that vascular invasion, degree of nuclear atypia, mitotic count and prominence of necrobiotic cell nests (cells with pycnotic nuclei and eosinophilic cytoplasm) are associated with malignancy. However, neoplasms in which above mentioned criteria of malignancy are not detected may also give rise to metastases. Hence benign appearing SPNs must be classified as lesions of uncertain malignant potential and must be operated on. Here we present a 27-year-old lady with 3 cm space occupying lesion in the head of the pancreas. Endoscopic ultrasonography guided biopsy revealed Solid Pseudopapillary Tumor of pancreas. Pancreaticoduodenectomy was carried out without significant complications and she was discharged on post-operative day 7. As this is a very rare tumor one encounters, we thought of reporting it.

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