Nine new fluorine containing 5‐amino‐1,3‐disubstituted pyrazoles have been synthesized and characterized by spectral studies. Condensation reactions of these 5‐amino‐1,3‐disubstituted pyrazoles with fluorinated 1,3‐diketones in the presence of glacial acetic acid have been studied and the structures of the resulting 1H‐pyrazolo[3,4‐b]pyridines have been confirmed by ir, pmr and 19F nmr spectral studies.

The condensation products of 5‐amino‐1,3‐disubstituted‐pyrazoles with aromatic aldehydes were identified as 2,4‐dihydro‐2,5‐diphenyl‐4‐(phenylmethylene)‐3H‐pyrazol‐5‐imine derivatives Treatment of these products with mercaptoacetic acid gave new fluorine containing 1H‐pyrazolo[3,4‐e][1,4]thiazepin‐7‐ones.

The pyrazolopyridines (III) are obtained by coupling the aminopyrazoles (I) with the diarylpropenones (II).

Das aus α‐Formylbenzylcyanid (I) mit Hydrazinhydrat (II) zugängliche Aminophenylpyrazol (III) liefert beim Diazotieren das Diazoniumsalz (IV).

Durch die Reaktion des Aminopyrazolons (I) mit lß‐Dicarbonylverbindungen (II) werden die im Titel genannten Heterocyclen (III) hergestellt, deren Wirkung auf das Zentralnervensxstem übergrüft wird.