Increased rate of non-union of Type II Odontoid fractures with rigid external orthosis have been reported. Recently technique of direct anterior screw fixation of the odontoid fracture is being advocated. Here we report the results of 13 cases of Type II dens fracture treated by the above method with an age group ranging from 17 to 73 years. An approach identical to the anterior cervical discectomy was used. Guide tube system devised by Synthes®, single image intensifier and Langenberg retractors was used to place a single cannulated screw through the fracture from C2 body into the dens. Among the 13 cases operated, in 11 cases we were successful. In one case while dissecting the fracture site CSF leak occurred and in another case the guide wire broke leading to abandoning to screw placement. There was no other complication due to the surgical procedure. The follow up period ranged between 2 months to 3 1/2 years. There were no neurological complications or screw fracture. In 9 of the 11 cases (82%) either bony union or fibrous unions have occurred. These results indicate that direct anterior single screw fixation has proved to be a very successful treatment.
Anterior cervical location of arachnoid cyst is a rare and only 22 cases have been reported in the literature. The surgical approach was quite varied and mostly these cysts were accessed via dorsal laminectomy, with few patients developing postoperative neurological deficit. We report a 51-year-old male with a cervical arachnoid cyst extending from the dens to the inferior border of the C3 body, which was successfully decompressed via an anterior cervical approach through the partial corpectomy of C2. This is probably the first case report demonstrating the safety of anterior partial median corpectomy of the C2 body with micro discectomy of C2-C3 space for excision of the anterior cervical archnoid cyst. The additional advantage of this procedure is that it may not result in spinal instability.
Introduction: Aspergillosis of the central nervous system is an uncommon infection, mainly occurring in immunocompromised patients with a high mortality. Surgical excision of the intracranial lesion combined with oral voriconazole has been proposed to improve the outcome in immunocompromised patients. Itraconazole has been considered not to be effective because of poor penetration into the brain tissue. We report the long-term outcome of 3 cases of intracranial aspergilloma in immunocompetent patients who were successfully treated with radical surgery combined with oral itraconazole.
Materials and Methods: This is a retrospective study in which chronic invasive intracranial aspergilloma was successfully treated in 3 apparently immunocompetent patients and followed-up for more than 5 years.
Results: Near complete or radical surgical removal of this localised chronic invasive intracranial aspergilloma whenever possible is the definitive treatment. When combined with the oral antifungal drug itraconazole, the management regimen is effective in achieving near complete long-term cure of more than 5 years. Oral itraconazole 200 mg twice daily should be given for a prolonged period of at least 6 months.
Conclusion: In chronic invasive intracranial aspergilloma in an immunocompetent patient, it was suggested that radical excision of the intracranial aspergilloma combined with oral antifungal drug belonging to triazole group that can be either itraconazole or voriconazole given for a period of 6 months was likely to improve the long-term outcome.
Key words: Central nervous system aspergillosis, Aspergilloma, Itraconazole, Voriconazole
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