Patients with ARMD demonstrated focal accumulation of fluorescent material most likely lipofuscin. Thus, the scanning laser technique combined with an image analyzing system may help to identify eyes at risk for developing exudative ARMD.
Aims-To determine whether indocyanine green (ICG) guided laser photocoagulation of occult choroidal neovascularisations (OCNV) is beneficial for patients with occult choroidal neovascularisation secondary to age related macular degeneration (AMD). Methods-A prospective pilot study was performed in 21 eyes with OCNV secondary to AMD that could be identified extrafoveolarly or juxtafoveolarly in an early ICG angiographic study. Laser photocoagulation was applied to the neovascular membrane identified in the early ICG angiographic study. Conclusion-This preliminary study of ICG guided laser photocoagulation of occult extrafoveal and juxtafoveal choroidal neovascularisations suggests that this technique may improve the visual prognosis of these patients. Further prospective controlled studies are necessary to confirm these data. (Br J Ophthalmol 1999;83:168-172) Age related macular degeneration (AMD) is the most common cause of vision loss in the Western world.
Results-Visual
The ophthalmologic examination especially the fluorescein angiography revealed no pathologic findings in patients with amaurosis fugax. The risk factor distribution corresponded to data found in patients with retinal artery occlusion.
The present study demonstrates that retinal hemodynamics are stable over a one year follow-up in healthy subjects. There are not significant changes to expect in retinal hemodynamics assesses in healthy subjects in one year under constant conditions. The knowledge of the intra- and interindividual variation of retinal blood flow indices allows a correct interpretation of pathophysiologic and pharmacological changes in retinal macro- and microcirculation.
Fluorescein angiography allows the quantification of number and area covered by cystoid formations in patients with diabetic macular oedema. There is a significant correlation of visual acuity to the area covered by these cystoid changes. The distance of cysts from the center of the FAZ does not correlate significantly to visual acuity. These measurements can prove useful in following cystoid changes and in monitoring the effect of currently used therapy regimen.
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