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Purpose: Usually any research survey can produce better results if it is utilized in local language. The study aimed to measure the inter-consistency, reliability and validity of three measures in Arabic language. Current study is phase I of research project to validate the measures in Arabic language.Material and Method: These three valuable and most widely used scales, Rosenberg self-esteem scale, brief psychological well-being scale and impact of weight on quality of life questionnaire were translated in Arabic language by adapting standard procedure of translation. Data was gathered from female students (N=500) enrolled in bachelors program during the period of November 2014-October 2015.Results: Reliability of the scale was calculated using Cronbach alpha. Psychological well-being scale was found having high reliability of 0.92, whereas, Rosenberg self-esteem scale and Impact of weight on quality of life questionnaire was found having acceptable range of reliability (0.72). All the sub scales of IWQOL-Lite reliability ranges from 0.87-0.95. Three of the scales were found having good content and construct validity.

The frequency of transfusion was increased in patients who developed alloantibodies. Typing patients and donors to match for Rh and Kell antigens would prevent more than 90% of RBC alloantibodies and reduce the frequency of transfusion in thalassemia patients.

Summary Objective The aim of this study was to assess abnormality of coagulation and anticoagulation parameters in dengue fever patients and the impact of these tests on the management of patients. Background Dengue fever is endemic in Pakistan with seasonal rise in cases. Morbidities and mortalities are proportionately reported to be increasing and associated with disseminated intravascular coagulation resulting in haemorrhagic or thrombotic manifestations in patients having deranged coagulation profiles. Methods/Materials This observational and descriptive study was conducted on confirmed Dengue patients at the National Institute of Blood Diseases during the years 2013 to 2016. Patients of all age groups were included in this study. Results were analysed by SPSS version 23. Results A total of 200 patients were selected with the mean age being 28.68 years (±13.28) and male predominance (147/200). The mean platelet count, haemoglobin and haematocrit at base line for bleeders and non‐bleeders showed significant results, where platelet count at baseline for bleeders was 24 000, whereas for non‐bleeders it was 29 000 and it showed significant correlation with bleeding (P‐value .027). Platelets were transfused to 76 (38%) patients. However, none of the specialised haemostasis parameters beside the platelet count correlated with bleeding, requiring platelet transfusions. Conclusion Our study showed a significant association of platelet counts, haemoglobin and haematocrit with bleeding. It can be concluded that coagulation and anticoagulation profiles will not benefit the management of dengue patients and in countries like Pakistan, it will only add to the economic burden on the patients.

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