V. A. Lasman scite author profile

A method for monitoring the manufacture of genetically engineered human insulin by HPLC was developed. The method was validated by the estimation of its linearity, correctness, accuracy, specificity, and stability; the limits of detection and quantitative assessment were also determined. It was proven that HPLC analysis enables reliable and reproducible results to be obtained and can be used for monitoring insulin manufacture.

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V. A. Lasman

Size-exclusion chromatography based on silica-diol for the analysis of the proinsulin fusion protein

Methods for protecting silica sorbents used in high-performance liquid chromatography from strongly adsorbed impurities during purification of human recombinant insulin

Displacement effect during HPLC preparative purification of human insulin

Validation of a method for monitoring the manufacture of human insulin

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