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The innate immunity system plays an important role in antitumor protection, and more and more attention has been paid to its study recent years. However, the interrelation of the effect or subpopulations of the cells of the innate immunity in bone marrow with clinical parameters is poorly studied. The paper presents data on the composition of innate immune cells in the bone marrow of 64 patients with operable breast cancer, as well as 10 women with benign processes in the mammary gland. As result a significant correlation between the molecular subtype of cancer and the level of B1- lymphocytes was identified. Breast cancer patients levels of NK cells (CD56 + CD3- and CD16 + CD3-) in the bone marrow were significantly higher in patients with low proliferative activity (Ki-67 less than 20%), compared to patients having a high tumor proliferation index. Populations of NK cells were interrelated with erythropoiesis in patients with breast cancer and were significantly higher in cases of reduced basophilic and polychromatophilicnormoblasts.

The article presents the results of a study about the features of pre-service teachers’ professional reflection. The average statistical results of the pre-service teachers who were the participants of the Olympiad “I am a professional” are considered in the context of students’ professional pedagogical reflection development. The research is based on the concept of three reflection functions: research, criticism and redesign, three types of reflection: prospective, situational, retrospective, the universal competences of a teacher: cognition skills, interaction skills, self skills. The study about the features of students’ professional reflection was carried out in 2021 during the period of the Olympiad “I am a professional” in the framework of three stages: planning/design, self-assessment/reflection, delayed group reflection. The sample included 261 students from universities in Moscow and other Russian regions, and 78 independent experts among acting school teachers. The methods of questioning (oral and written), content analysis, case studies, focus groups, video analysis, observation were used. As a result, the following features of students’ reflection were revealed, such as: the contradictory nature of goal-setting and the determination of the necessary conditions and means when planning a lesson; the tendency to overestimate their professional strengths and not notice insufficiently formed competencies; the tendency to give exaggerated importance to the technical aspects; misunderstanding of the professional pedagogical language against the background of an intuitively adequate understanding of many pedagogical and psychological phenomena, etc. From a practical point of view, the results obtained make it possible to identify the area of professional deficiencies of pre-service teachers and set the focus for a closer examination and more thorough extensive study of evaluative, critical and other complex thinking skills, which provide a thorough professional reflection. In this regard, reflective-analytical and reflective-design work formats become significant both in the educational process and in the practical training of pre-service teachers.

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Introduction. The development of professional reflection is determined by the nature of the activity in relation to which it is carried out. At the same time, teacher professional reflection is an effective resource for the development of educational activities. At the present stage, there is a wide variety of education models. Each educational model is characterised by its special values; reflection has its own special meaning, purpose, and result in a specific educational model.Aim. The current research aims to present the authors’ model for studying the features of teacher professional reflection; to discuss the results of testing this research model, which made it possible to draw a number of conclusions about the presence and nature of the relationship between the level of teacher professional reflection and their personal and professional values.Methodology and research methods. The present research is based on the activity approach, theoretical provisions on the structure and functions of reflection of activity, the meaning of reflection in various models of education, the types of professional pedagogical reflection. The research model is developed through the questionnaire method and the case method. The study involved primary and secondary school teachers of three educational complexes in Moscow (N = 63).Results. It has been established that the values of the life and professional plan of the subjects are consistent with each other, and professional actions are generally not related to the declared professional values. The authors confirmed the hypothesis that the reflection of positional type has a significant positive relationship between the degree of congruence between the values declared in the survey and those manifested in solving problematic professional situations and the level of development of reflection of these types.Scientific novelty lies in the development of a model for studying the features of professional reflection associated with the personal and professional values of the teacher. The results obtained in the course of its approbation can serve as a basis for understanding the mechanisms for the development of professional reflection of teachers in various models of education.Practical significance. The developed methodology for studying the features of professional reflection of teachers can be used for the further creation of the set of tools for self-assessment and the development of professional pedagogical competence, the core of which is pedagogical reflection.