The treatment of burn disease presents significant difficulties. Particularly high mortality (51.7% - 64.4%) occurs during the period of acute burn toxemia, characterized by pronounced intoxication of the body. According to the toxic theory of burn toxemia pathogenesis, it is determined by the toxicity of blood, lymph, extracts from the skin and internal organs, fluid blisters burned. This theory is recognized by most combustiologists; researchers differ in their opinions only in assessing the nature of the toxin and the place of its formation.

Goal. Implementation of the requirements of the EU Directives in the legislation of Ukraine on the safety of fertilizers and fertilizers.Object and methods of research. Fertilizers and fertilizers, sewage sludge of the food industry, methods of analytical hygienic analysis.Research results and their discussion. In accordance with the Decree of the President of Ukraine and the relevant order of the Prime Minister of Ukraine and the Decision of the National Security and Defense Council of Ukraine "On measures to improve chemical safety in Ukraine" were instructed to develop and approve technical regulations documents (EU). Basically, the Regulation of the European Parliament and of the Council /2019/1009 of 05.06.2019) corresponds to the "Law of Ukraine on Pesticides and Agrochemicals" (of 02.03.1995 with changes). All fertilizers and products for their production according to the provisions of EU regulations are characterized as products whose function is to provide plants or fungi with nutrients. Fertilizers are substances that are designed to increase the efficiency of plant nutrition. Fertilizers by purpose are divided into organic, organic-mineral, inorganic fertilizers, which in turn are divided into groups depending on their physical and chemical condition and individual purposes.Many years of research on the use of fertilizers in Ukraine have shown that in previous years, mostly mineral fertilizers were used. Their residues and components formed during decomposition were high levels of pollution of the environment, especially soil, water sources, air, especially due to excessive use of nitrogen-containing mineral and organic fertilizers.Currently, in connection with the development of farms for growing pigs, poultry there is an accumulation of waste from their lives. Organic waste is also generated in the food industry: dairy-, alcohol-and sugar factories. Due to the origin and conditions of formation of these substrates, which are not always characterized by compliance with the requirements of full fermentation and composting, there is a risk of contamination of substrates with pathogenic microorganisms and helminthes, which poses an epidemiological threat.Comprehensive studies of sludge from wastewater treatment plants of a dairy plant based on the results of sanitary-chemical