Медицинский институт ФГБОУ ВПО «МГУ им. Н. П. Огарева», г. Саранск 2 Медицинский институт ФГБОУ ВПО «Пензенский государственный университет», г. Пенза Важнейшими триггерными механизмами мембранодеструктивных явлений при остром панкреатите являются активизация перекисного окисления мембранных липидов, циркуляторная и тканевая гипоксия. Применение антиоксидантной терапии при остром экспериментальном панкреатите снижает интенсивность перекисного окисления липидов (уровень диеновых конъюгатов статистически значимо снижается на 30,4-32,5%) и восстанавливает тканевое дыхание (окислительно-восстановительный потенциал выше контроля на 10-15%). На микроциркуляцию такого рода терапия оказывает меньшее влияние.
Midline hernia is a pathological condition that is characterized by a protrusion of some internal organs through the holes in the aponeurotic plate of the abdominal raphe.
The presented analytical study provides information on the likely risk factors for hernia formation, the assessment of which remains relevant today. Besides, the authors examine diagnosis and classification of midline hernias and describe the advantages and disadvantages of the proposed surgical methods of hernia treatment. Despite a large number of proposed surgical methods for midline hernia correction and treatment, all of them have certain disadvantages, mainly associated with a high incidence of reherniation and postoperative complications. The choice between the proposed methods of hernia orifice closure and intraoperative midline strengthening to prevent reherniation is important for any surgeon.
The information search for the literature review was performed on the platforms elibrary.ru and pubmed.ncbi.nlm.nih.gov.
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