A problem of social sequences of lung tuberculosis has not been reflected in the literature. This study was aimed to investigate social sequences of tuberculosis. We examined a continuous sample of 100 patients with lung tuberculosis (LT) while being treated in a hospital, of them 62 males and 38 females aged 22 to 56 yrs. Fifty patients had infiltrative LT, and other 50 ones had fibrocavitating LT. The diagnosis was reached based on typical clinical, radiological, laboratory, and functional investigations. A special questionnaire was developed to study social sequences of LT. Results showed social isolation is typical for both the newly diagnosed LT patients and chronic LT. The fibrocavitating LT patients experienced negative attitude of relatives and community, worsening working conditions and narrowing fields of interest. The infiltrative LT patients were characterized by changes in marital status and disorders of living plans. Therefore, all LT patients experience social sequences of the disease.

The problem of lowering adherence to therapy in lung tuberculosis patients and abilities to enhance motivation to for treatment has not been highlighted in literature. The aim of this study was to investigate factors influencing the adherence to treatment in tuberculosis patients and abilities to enhance their motivation for treatment. A total sample of 72 inpatients with infiltrative and firbocavernous lung tuberculosis were involved. They were residents of Samara region aged 22 to 56 yrs. To investigate factors reducing adherence to therapy a special questionnaire consisting of 34 points has been created proposed by Samara military medical university. Statistic analysis was performed using SPSS programme, version 12.0. As a result, the most common factors reducing adherence to therapy in lung tuberculosis patients were adverse effects of antituberculosis drugs, financial problems, complications of the disease and fear of their appearance, painfulness of treatment procedures, tiredness of long treatment period and of hospital environment. To overcome the fear education of the patients is necessary. To reduce the emotional component and painfulness of some treatment procedures, manual and audiomethods could be helpful. Effective therapy, confidence in the attendant physician and full information of the disease could enhance motivation to treatment.

A pilot study was designed to analyze causes of late diagnosis of lung tuberculosis and late start of the specific therapy. Thirty-eight inpatients with proven infiltrative lung tuberculosis were randomly involved in the study; they were city and rural dwellers of different age. A special questionnaire was developed to determine reasons of late diagnosis. An analysis of results obtained has shown that 8 patients, or 21 % were diagnosed at a scheduled large frame photofluorography, 30 % of the late diagnosed patients were not aware of their disease, 25 % of the females and 64 % of the maleswere self-treated. Primary care therapeutists were blamed for the late diagnosis in 33 % of the patients while failed to perform necessary investigations; the delay was 2 to 11 months.

As many as 42 patients with chronic obstructive bronchitis, 24 men and 18 women were treated with Ingacort during 8 weeks. 30 patients with clinical signs of lower respiratory ways infection were given Asitromicin (Sumamed) for 5 days. All patients were divided into two groups depending on age and duration of the disease. Ingacort is recommended as a basic therapy for patients with chronic obstructive bronchitis.