The present study was carried out to determine the quality of life in regional cancer patients of Hyderabad city with an objective to create awareness about the various health related issues and financial problems underlying the disease. So that possible measures can be taken by the society and the government in advance to improve the quality of life in cancer patients. The complete data for the present study has been collected for a period of 2 months from Mehdi Nawaz Jung Institute of Oncology and Regional Cancer Centre, Red Hills, Hyderabad, Telangana, India from 192 Females and 32 Males in the age group between 18-70 years. The quality of life of the cancer subjects was assessed using EORTC QLQ-C-30 questionnaire. The observations have shown that the cancer patients in spite of having better functioning and minimum symptoms, their perception was that they had poor quality of life. It is concluded that the therapy should be individualized for each patient not just based upon the type or stage of cancer but also based on the patient's priorities, concerns and symptoms along with treating the disease. In simple words it can be said that the therapy should be patient oriented rather than disease oriented.