Objective. The aim is to find out the common and different features of the clinical course of erysipelas from other diseases that can imitate it. Materials and methods. 114 case histories of patients who were hospitalized in the center of purulent-septic surgery in the City Hospital No 3 in Zaporizhzhia for the period 2019-2020 were analyzed. 123 patients, who underwent hospital treatment in the center during this period of time, were with post-injection abscesses of soft tissue, 184 - with soft tissue abscesses, 203 - with phlegmons of various localizations, 49 - with complicated panaritium, 3 of which - subcutaneous. Over the past 5 years, 127 patients were consulted in the clinic and other therapeutic, infectious, neurological and other departments of the city. A number of criteria and signs have been identified to differentiate erysipelas from diseases that may have similar clinical symptoms and a number of circumstances that need to be clarified. Results. It is established that the diagnosis of erysipelas does not require special laboratory examination and is made on the basis of examination of the patient, epidemiological history and medical history. Provoking factors in the development of erysipelas are: violation of the integrity of the skin (abrasions, scratches, abrasions, cracks, bruises, injuries); mycoses; a sharp change in temperature (supercooling, overheating); emotional stress; increased insolation. Erysipelas has a characteristic summer-autumn seasonality. In people engaged in physical labor, the disease is registered more often than in other types of work. Hereditary predisposition to the disease is observed in 10-15% of cases. In this regard, the presence of such factors as congenital and acquired venous insufficiency of the lower extremities, fungal infection of the lower extremities, the presence of postoperative and post-traumatic scars, lymphostasis, diabetes, cardiovascular disease and diseases accompanied by the development of edema, intake of corticosteroids or cytostatics are of essential significance in the development of the disease. Conclusions. Mathematical modeling between erysipelas and other diseases that have similar syndromes in their clinical picture may be useful in making a differential diagnosis between them.

Purpose. The purpose is to find out the common and different features of the clinical course of erysipelas from other diseases that can imitate it. Materials and methods. 114 case histories of patients who were hospitalized in the center of purulent-septic surgery in the Non-profit municipal enterprise “City Hospital № 3” in Zaporizhzhia for the period 2019-2020 were analyzed. 123 patients, who underwent hospital treatment in the center during this period of time, were with post-injection abscesses of soft tissue, 184 - with soft tissue abscesses, 203 - with phlegmons of various localizations, 49 - with complicated panaritium, 3 of which -  subcutaneous. Over the past 5 years, 127 patients were consulted in the clinic and other therapeutic, infectious, neurological and other departments of the city. A number of criteria and signs have been identified to differentiate erysipelas from diseases that may have similar clinical symptoms and a number of circumstances that need to be clarified. Results. It is established that the diagnosis of erysipelas does not require special laboratory examination and is made on the basis of examination of the patient, epidemiological history and medical history. Provoking factors in the development of erysipelas are: violation of the integrity of the skin (abrasions, scratches, abrasions, cracks, bruises, injuries); mycoses; a sharp change in temperature (supercooling, overheating); emotional stress; increased insolation. Erysipelas has a characteristic summer-autumn seasonality. In people engaged in physical labor, the disease is registered more often than in other types of work. Hereditary predisposition to the disease is observed in 10-15% of cases. In this regard,  the presence of such factors as congenital and acquired venous insufficiency of the lower extremities, fungal infection of the lower extremities, the presence of postoperative and post-traumatic scars, lymphostasis, diabetes, cardiovascular disease and diseases accompanied by the development of edema, intake of corticosteroids or cytostatics are of essential significance in the development of the disease. Conclusions. Mathematical modeling between erysipelas and other diseases that have similar syndromes in their clinical picture may be useful in making a differential diagnosis between them.

Purpose of the study. Improve postoperative treatment of phlegmonous and necrotic forms of erysipelas by alternating HAC therapy of wounds and staged necrectomies, reduce the time of cleaning and preparation of the wound for dermatoplasty. Materials and metods. The results of treatment of 87 patients with complicated forms of erysipelas who were treated in the purulent-septic center of KNP «City Hospital № 3» in Zaporozhye for the period 2020–2021 were analyzed. Results. The effectiveness of treatment, including topical therapy, was evaluated by improving laboratory parameters (leukocyte formula), the number of microbial bodies per 1g of tissue and the duration of wound cleansing. In the phlegmonous form of erysipelas, normalization of the leukocyte formula was observed on day 3, which is probably faster than among patients in the control group – on day 4 (t = 4,01375; P = 0,000182). In patients with necrotic form of erysipelas in the main group, the normalization of the leukocyte formula occurred probably faster, almost 2 days, than in the control group – 4 and 6 days, respectively (t = 2,16682; P = 0,042499). At the same time there was a decrease in microbial contamination of wounds. The terms of wound cleansing in the postoperative period in patients of the main group were probably shorter than in patients of the control group – by 1,87 ± 0,23 days in phlegmonous form (t = 3,75213; P = 0,000320) and 2,89 ± 0,34 in necrotic (t = 2,33969; P = 0,026659). Conclusion. Improvement of postoperative local treatment of patients with phlegmonous and necrotic forms of erysipelas allowed to significantly reduce the length of stay of patients in the hospital by 3,26 ± 0,43 days (t = 6,47461; P < 0,000001).