Background: Thyroid nodules are common endocrine problem. A discrete swelling in an otherwise impalpable gland is termed as solitary nodule of thyroid. Solitary nodules have a high likelihood of being malignant. They should be characterized properly for optimum management. Aim of the study is to identify the incidence of malignancy in solitary nodule thyroid.Methods: A prospective study had been carried out from January 2018 to October 2018, in the Department of General surgery, ACS Medical College and Hospital, Chennai, India. Fifty patients, who presented with solitary thyroid swelling were examined clinically and confirmed after taking a detailed history and underwent thyroid surgery were included in this study. The histopathological reports were evaluated by standard statistical methods.Results: There were 50 cases of clinically detected solitary thyroid nodule with female preponderance more than males. The mean age of the incidence of solitary thyroid nodule is 35years. The incidence of malignancy in solitary thyroid nodule is 20%.Conclusions: It is concluded from the present study that 20% of solitary thyroid nodules are malignant, with female preponderance and a mean age of solitary thyroid nodule is 35years.

Background:The aim of the study was to evaluate an association of serum lipid profile in women with benign breast disease and to analyze a possible relationship between serum lipid profile and benign breast diseases with emphasis to laboratory findings. Methods: Hospital based study carried out at ACS Medical College, Chennai, during the period of June 2018 to November 2018. 75 women in General Surgery ward/outpatient were included in the study. Subjects included in the study were women of age between 16 to 35 years, provided they fulfilled inclusion and exclusion criteria. History was noted, serum lipid profile was done. Results were noted and analysed. Results: Out of 75 subjects, 21.3% of women with benign breast disease were having elevated serum lipid profile. Conclusions: It is concluded that benign breast disease is associated with altered serum lipid profile namely hyperlipidemia. Therefore, routine screening and treatment of this condition is must among women with benign breast disease by dietary management, use of anti-hyperlipidemic drugs to achieve long lasting cure and to prevent possible future recurrences.