We studied the photodynamic inactivation of E. coli, S. aureus, and P. aeruginosa in vitro. Bacteria suspensions were incubated with riboflavin and exposed to blue light emitted by a diode matrix. Exogenous photosensitizer riboflavin efficiently inactivated bacteria, while methylene blue was ineffective. Under the effect of blue light in a dose of 117 J/cm(2), photoinactivation of E. coli, S. aureus, and P. aeruginosa occurred without photosensitizer riboflavin.

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In patients with chronic arterial insufficiency of the legs pentoxyphyllin drugs not change blood viscosity. By contrast, photohemotherapy with blue light decreased and normalized blood viscosity in 64% patients.