Bioactive compounds comprising secondary metabolites produced by endophytic fungi have wide applications in pharmacology and agriculture. Isolation, characterisation and evaluation of biological activities of secondary metabolites were carried out from Cochliobolus kusanoi an endophytic fungus of Nerium oleander L. The fungus was identified based on 18S rDNA sequence analysis. There are no reports available on the compounds of C.kusanoi hence, antimicrobial metabolite produced by this fungus was extracted and purified by fractionation using hexane, diethyl ether, dichloromethane, ethyl acetate and methanol. Out of all the solvent fractions, the methanol fraction exhibited better antimicrobial activity which was further purified and characterised as oosporein. Oosporein from C.kusanoi exhibited broad spectrum in vitro antimicrobial, antioxidant and cytotoxic activities. The characterisation and antioxidant activity of oosporein from C. kusanoi are reported for the first time.

Medicinal properties of plants derivatives from natural products have wide range of pharmacological significance. The properties of papaya (Carica papaya) fruit and other plant parts are well known in traditional system of medicine and also known for food and nutritional values throughout the world. During the most recent decades significant advancement has been accomplished in regards to the biological activity and medicinal use of papaya, additionally, it is considered as profitable nutraceutical natural product plant. In this current review discussed with medicinal properties of C. papaya.