Zebrafish are increasingly becoming popular as promising new model species for translational research in a variety of neurological fields. Because of their complex behaviors across all major neurobehavioral domains and strong genetic and physiological similarities to humans, zebrafish are well-suited to modelling many aspects of anxiety-related states. In this paper, we first summarized the behavioral models available in zebrafish, such as novel tank test, light/dark box test, open field test, and social preference test, and their efficacy in discovering anxiety-like indices in zebrafish, followed by highlighting the key neurotransmitter systems, such as glutamate and GABA. In addition, cortisol levels and gene expression were explored as well. Overall, this review discusses the benefits of using the zebrafish model for anxiety research and examines current research in the field.

Rheumatoid arthritis (RA) is a chronic inflammatory disorder in which the immune system attacks the body's tissues, including joints, whereas Covid19 is an acute respiratory sickness caused by a virus that affects the immune system and can produce a variety of symptoms as well as death in some cases. A higher frequency of autoimmune inflammatory arthritis has been associated with respiratory diseases caused by various viral infections and these infections can cause flare-ups in inflammatory arthritic patients. The study focuses on the link between Covid19 and Rheumatoid arthritis as well as the various drugs used to treat the disease and their effects on the human body. The numerous comorbidities, as well as the impact of drugs and vaccination on individuals, were discussed. People affected with RA are already at risk of infection due to the disease itself or the conditions brought about by the treatment of drugs or due to several clinical opinions and therapies. The data from various research explains the prevalence of COVID19 symptoms in rheumatoid arthritis patients is more than twice that of the effect.