A validated HPLC method was developed for the determination of Busulfan (BUS) in pharmaceutical formulation.It is a new simple, accurate, precise and reproducible HPLC method has been developed for the estimation of Busulfan (1,4-butanediol dimethanesulfonate) in its inject able dosage.The method developed in High Performance Liquid Chromatographic method using suitable column (YMC Pack ODS-A (150 x 4.6) mm, 3µm). All the components of the system are controlled using SCL-10Avp System Controller. Data acquisition was done using LC Solutions software.The method was validated as per the ICH guidelines. Thus, the proposed HPLC method can be successfully applied for the routine quality control analysis of formulations. The method developed is simple and is better than the methods reported in the literature and the method is capable to give a good detector response, the recovery calculated was within the range of 98% to 102% of the specification limits.

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Advances in nanoscience and nanotechnology are centered in the control of size and shape of nanoparticles, as well as attainment of the extended arrangement of nanoparticles in different structures. One dimensional nanostructured magnetic materials are interesting because of their enhanced magnetic properties and potential applications such as information storage and gas sensor. The advanced electronic applications of Fe3O4 magnetic nanomaterials are considered to require improvement in the powder processing, particularly, meticulous particle control in the nanometer range and phase purity. Structural properties of Fe3O4 nanoparticles were synthesized via sol-gel protocol, the morphology and particles size were determined by X-ray diffraction, scanning electron microscope, transmission electron microscope, energy dispersive X-ray, UV-diffuse reflectance spectrophotometer and particle size analyzer. The structure of as prepared Fe3O4 nanoparticles was used for photocatalytic applications.

A novel, simple and economic high performance liquid chromatography (HPLC) method has been developed for the estimation of Clofarabine in bulk and tablet dosage form with greater precision and accuracy.The method was validated as per ICH guidelines. Validation studies demonstrated that the proposed HPLC method is simple, specific, rapid, reliable and reproducible. Hence the proposed method can be applied for the routine quality control analysis of Clofarabine in bulk and tablet dosage forms. All the components of the system are controlled using SCL-10Avp System Controller. Data acquisition was done using LC Solutions software.