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Introduction: The study of the prevalence of narcological disorders is an integral part of the monitoring of the drug situation allowing identification of the main trends in the situation with the use of narcotic drugs. Objective: To analyze the level and structure of non-medical use of prescription drugs among the population of the Republic of Crimea and to assess their dynamics in 2020–2021. Materials and methods: The subject of the study was quantitative indicators characterizing the spread of drug use disorders in the Republic of Crimea. The information base of the study included data and materials of the Federal State Statistics Service and the Ministry of Health of the Republic of Crimea. We processed data of the statistical reporting documentation for 2020–2021, Forms No. 37, Information on patients with alcoholism, drug addiction, substance abuse, and No. 11, Incidence of substance use disorders. Incidence and prevalence rates were estimated per 100 thousand population. The data were analyzed in Microsoft Excel. Results: We established an increase in the incidence of substance use disorders in the Republic of Crimea in 2020–2021 from 38.3 to 42.9 per 100 thousand population (by 12.01 % in the year 2021 compared to 2020) and an increase in the overall incidence of drug addiction and abuse from 566.5 to 578.3 per 100 thousand population (2.08 %). We noted a slight decrease in opium addiction, transition to new synthetic drugs, and an increase in the proportion of a combined use of narcotic drugs. Males aged 20 to 59 years predominate among drug users. Conclusions: Our findings show a consistently high prevalence of non-medical use of prescription drugs among the population in the Republic of Crimea, an increase in the incidence and prevalence of drug addiction and in the number of doctor’s visits among drug abusers, and a growth of drug overdose deaths.

The problems of planning, follow-up of pregnancy and childbirth in women with inherited extrapyramidal neurological disorders, including torsion dystonia, are represented by isolated cases and receive little literature coverage. Dystonia is a rare disease, the incidence of its various types is 300–400 patients per million (0.03%). Idiopathic torsion dystonia is a group of genetically determined hyperkinetic disorders, which refers to an extrapyramidal pathology of the central nervous system with a progressive course of the disease. This article presents the case follow-up of pregnancy and childbirth in a patient with torsion dystonia and chronic neurostimulation 1.5 years after implantation of the ActivaRC neurostimulation system without drug therapy. The patient has given birth via elective caesarean section while receiving neurostimulation via the ActivaRC system. This clinical observation shows that the physiological course of pregnancy in patients with this diagnosis is possible in case of its advance planning and correction of the DBS programming. A multidisciplinary approach to the management of a patient with generalized torsion dystonia and chronic neurostimulation made it possible to achieve a favourable pregnancy outcome for both mother and fetus. Follow-up of pregnancy in such patients requires a correction of the DBS programming and choosing the optimal timing and method for delivery. The routine follow-up clinical examination by a neurologist should be carried out both in the planning stage and throughout the entire period of pregnancy (end of the first trimester, weeks 21–23, 32–34), as well as in the postpartum period.