Microwave tomographic imaging is one of the new technologies which has the potential for important applications in medicine. Microwave tomographically reconstructed images may potentially provide information about the physiological state of tissue as well as the anatomical structure of an organ. A two-dimensional (2-D) prototype of a quasi real-time microwave tomographic system was constructed. It was utilized to reconstruct images of physiologically active biological tissues such as an explanted canine perfused heart. The tomographic system consisted of 64 special antennae, divided into 32 emitters and 32 receivers which were electronically scanned. The cylindrical microwave chamber had an internal diameter of 360 mm and was filled with various solutions, including deionized water. The system operated on a frequency of 2.45 GHz. The polarization of the incident electromagnetic field was linear in the vertical direction. Total acquisition time was less than 500 ms. Both accurate and approximation methods of image reconstruction were used. Images of 2-D phantoms, canine hearts, and beating canine hearts have been achieved. In the worst-case situation when the 2-D diffraction model was used for an attempt to "slice" three-dimensional (3-D) object reconstruction, we still achieved spatial resolution of 1 to 2 cm and contrast resolution of 5%.
The purpose of this study was to construct a microwave tomographic system capable of conducting experiments with whole scale biological objects and to demonstrate the feasibility of microwave tomography for imaging such objects using a canine model. Experiments were conducted using a three-dimensional (3-D) microwave tomographic system with working chamber dimensions of 120 cm in diameter and 135 cm in height. The operating frequency was 0.9 GHz. The object under study was located in the central area of the tomographic chamber filled with a salt solution. Experimentally measured attenuation of the electromagnetic field through the thorax was about -120 dB. To obtain images, we used various two-dimensional and 3-D reconstruction schemes. Images of the canine were obtained. In spite of imperfections, the images represent a significant milestone in the development of microwave tomography for whole body imaging and demonstrate its feasibility.
A method of image reconstruction in three-dimensional (3-D) microwave tomography in a weak dielectric contrast case has been developed. By utilizing only one component of the vector electromagnetic field this method allows successful reconstruction of images of 3-D mathematical phantoms. A prototype of the 3-D microwave tomographic system capable of imaging 3-D objects has been constructed. The system operates at a frequency of 2.36 GHz and utilizes a code-division technique. With dimensions of the cylindrical working chamber z = 40 cm and d = 60 cm, the system allows measurement of an attenuation up to 120 dB having signal-to-noise ratio about 30 dB. The direct problem solutions for different mathematical approaches were compared with an experimentally measured field distribution inside the working chamber. The tomographic system and the reconstruction method were tested in simple experimental imaging.
Photoelectron yields of extruded scintillation counters with titanium dioxide coating and embedded wavelength shifting fibers read out by silicon photomultipliers have been measured at the Fermilab Test Beam Facility using 120 GeV protons. The yields were measured as a function of transverse, longitudinal, and angular positions for a variety of scintillator compositions, reflective coating mixtures, and fiber diameters. Timing performance was also studied. These studies were carried out by the Cosmic Ray Veto Group of the Mu2e collaboration as part of their R&D program.
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