Aim of the study was to form target system of clinical correction, based on the analysis of pathogenesis factors of odontophobic reactions in children with autism.Materials and methods: 30 children with various dental diseases which had a concomitant diagnosis of autism spectrum disorders and showed odontophobic reactions were examined. The detection of odontophobic reactions was performed using the ethological method.The results of the search for targets for psychocorrection interventions at each level of presentation of each pathological phenomenon, which determine the development of odontophobic reactions in children with different levels of mental health, allow us to formulate a targeted model of adaptation to the conditions of dental admission.Conclusions: psychocorrection interventions aimed at leveling odontophobic reactions of stenic-negativistic, insulating and transaffective type in children with autism are formulated by modifying the basic phenomena of their pathogenesis (fencing, stereotypes, and anancasms).