Novel betacoronavirus is a recent threat to the global health. It has been identified as the cause of the outbreak of respiratory illness that originated in the city of Wuhan, China and has spread rapidly to several other countries within a short span of time. Transmission occurs through respiratory droplets or contaminated surfaces from an infected person, saliva of infected persons has also shown shedding of live virus. Clinical manifestations of COVID-19 can range from mild to severe and can even progress to ARDS and septic shock leading to death. All health care professionals including dental surgeons are at a high risk of acquiring the infection. Dental clinics and hospitals carry a high risk of cross-infection. Aggressive preventive and personal protective measures help in preventing exposure to the infection. Dental professionals should adopt various specific preventive methods and treatment strategies to prevent the spread of the infection in a dental setup.
Background: The present study aimed to report occurrence of radix entomolaris in mandibular first molar.
Materials and methods:The present study was conducted on 428 mandibular first molar in 280 patients. The incidence of RE and comparison of the occurrence between males and females and between the right and left sides of the mandible were recorded. Results: Out of 210 molars in males, 10 (4.76%) had and out of 218 molars in females, 8 (3.66%) had Radix Entomolaris. The difference was significant (P< 0.05). 12 Radix Entomolaris were seen in 238 left molars and 6 were seen in 190 right molars. The difference was significant (P< 0.05).
Conclusion:Authors found that Radix Entomolaris was commonly seen in males. Left side exhibited more Radix Entomolaris as compared to right side.
Recent advent of immune checkpoint inhibitors (ICIs) have made significant improvement in the treatment outcome of cancer patients. They are also known to increase the overall survival in many malignancies. They target key immune checkpoints, acting on the cytotoxic T-lymphocyte antigen-4, programmed death-1 (PD-1), and PD-1 ligand 1 pathways. ICIs are effective in cancer therapy, but also possess various adverse effects that are termed together as immune-related adverse events (irAEs). Information focusing only on the oral reactions of irAEs is scanty in the literature. Therefore, we performed a computerized database search in PubMed and Google Scholar to identify and collect data regarding the oral adverse effects of ICIs. The early recognition of oral irAEs and appropriative intervention may help in improving the quality of life in patients. This paper presents a brief review of oral irAEs and their management.
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