The purulent-septic infection caused by Staphylococcus aureus is one of the biggest problems of modern medicine. There are some strategies to control the increasing antibiotic resistance of bacteria. They are the development and introduction of new antibacterial drugs into surgical practice, the improvement of antimicrobial therapy methods and the rotation of antibacterial drugs [1, 2, 3]. Staphylococcus aureus is one of the most common causative agents of infections of various localizations. The development of mechanisms of antibiotic resistance of bacteria is more often determined by genes located on the bacterial chromosome or Rplasmids. Particular attention is paid to methicillinresistant staphylococci (MRS strains). They are registered in nosocomial or out-of-hospital infections. The resistance of staphylococci to β-lactam antibiotics is due to the presence of the mec A gene. It encodes the penicillin-binding protein (PBP). The mec A gene is located on a mobile genetic element. This element is called the staphylococcal chromosome cassette (SCCmec). Methicillin-resistant Staphylococcus aureus is resistant to all β-lactam antibiotics. Currently, it is necessary to use combinations of antibacterial drugs for the treatment of infections caused by methicillinresistant staphylococci.

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In work the results of investigations on development of new classes of the composition materials on the basis of appreted HPPE filled with various mineral fillers are presented. It has been shown that the synthesized ternary copolymers used in work as appretes due to polyfunctional composition allow to prepare the composition materials with high strength properties and adhesion. The results of exclusionchromatographic investigation of molecular characteristics of ternary copolymers synthesized at radical copolymerization of -olefins in a series С6-С8 with maleic anhydride and acrylic acid and also some physical-mechanical properties of polymer compositions modified by them are presented Keywords-highly filled polymer composition materials, polyethylene of high pressure, high-effective exclusion chromatography, molecular-weight distribution

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