No abstract

The state of erythrocytes fully reflects the level of functional capabilities of the body and can be considered a reliable marker of its general condition. The study was carried out on 32 healthy young men who had low stable physical activity for a long time and started swimming training in the pool 3 times during the week. The control group consisted of 38 healthy young men who, over the past 5 years, regularly went in for swimming 3 times a week. Standard hematological and statistical methods for performing scientific research were applied. After six months of swimming training in the blood of beginner swimmers, a normalization of the number of metabolites of arachidonic acid, a reduction in the composition of erythrocytes of cholesterol molecules and lipid peroxidation products, and an increase in the content of phospholipids in them was noted. In the blood of beginner swimmers, there was an increase in the number of erythrocytes with a normal shape, and a significant decrease in the number of erythrocytes with a changed shape was achieved. For the boys of the control group, who had been swimming for a long time, it turned out to be characterized by a high content of unchanged erythrocytes in the blood and the optimum of their biochemical parameters. It can be assumed that regular swimming lessons already after six months provide significant positive dynamics of the surface properties of erythrocytes in the blood, which significantly improves the implementation of microcirculation and intensifies metabolism throughout the body.

No abstract

The progression of aging affects various blood parameters, which can weaken the viability of the body. Clarification of various aspects of this process requires additional observations, especially with the use of animals. The study was conducted on 43 healthy outbred male rats aged 24 months. Also, 32 healthy outbred male rats 3 months old, which formed the control group, were taken under observation. The examined 24-month-old rats showed standard aging phenomena. In their erythrocytes, there was an increase in lipid peroxidation caused by a weakening of the activity of their antioxidant defense. In the blood of two-year-old rats, there was a decrease in the level of erythrocyte-discocytes. This was accompanied in them by an excess content of erythrocytes in the blood, which had a changed shape to varying degrees. In rats of the older group, erythrocyte aggregation was increased, as indicated by an increase in the numberof erythrocytes that entered the aggregates in the blood and an increase in the number of most erythrocyte aggregates with a decrease in the level of free erythrocytes. For two-year-old rats, low content of erythrocytesdisconcytes in the blood and an excess number of erythrocytes with a modified shape, as well as an increase in their aggregation, are characteristics. An important reason for these changes is the weakening of the antioxidant protection of erythrocytes, leading to a pronounced activation of lipid peroxidation in them.