Aim To analyze the sex-specific incidence and mortality trends of brain malignancies in Croatia from 2001 to 2014. Methods Incidence and mortality rates per 100 000 population were calculated using data obtained from the Croatian National Cancer Registry and the Croatian Bureau of Statistics. Rates were age-standardized to the European Standard Population, and trends were assessed using joinpoint regression. Results In the observed period there were 6634 new brain malignancy cases (52% men) and 5379 deaths due to this diagnosis (52% men). Age-standardized incidence rates ranged from 9.2-11.5 per 100 000 in men and from 7-8.8 per 100 000 in women. Mortality rates ranged from 7.5-8.7 per 100 000 in men and from 5-6.5 in women. Incidence trends in men, mortality in men, and mortality in women were not statistically significant, while a significant trend was observed in incidence in women (annual percent change -1.5; 95% confidence interval -2.3 to -0.6). No joinpoints were observed in any of the joinpoint analyses by sex for incidence and mortality. Age-specific incidence and mortality rates in both sexes indicate a trend shift toward older age. The proportion of morphologically verified cases ranged from 40.2%-62.4% in men and from 38.6%-56.3% in women; the proportion of death-certificate-only cases ranged from 3.3%-9.4% in men and from 3.3%-17.5% in women. Conclusion Incidence and mortality of brain malignancies in Croatia are among the highest in Europe, while reporting on brain malignancies is still poor. There is a need for improved care of patients with brain malignancies and detailed and accurate data reporting.

Introduction. Comprehensive care for patients who no longer respond to treatment procedures is called palliative care. Palliative medicine does not delay or accelerate death, it promotes life, and considers dying as a normal process. In palliative medicine and care there is no place for hierarchy - teamwork, focus on the patient and respect for his autonomy are what is important. Aim. The conducted research shows the knowledge of nurses about palliative care at the primary, secondary and tertiary levels of health care. Methods. Prospective research in the Republic of Croatia at three levels of health care has been conducted. The sample included 150 nurses. The instrument used in the study was the Palliative Care Quiz for Nursing (PCQN). Results. The results showed that the nurses’ knowledge of palliative care is insufficient among the nursing population. Despite numerous training activities conducted over the past ten years, levels of knowledge are still lower than expected. Nurses at the primary level of health care have far greater knowledge than nurses at secondary and tertiary levels. Conclusion. Results of the study showed the need for quality education with real-life examples in order to achieve higher levels of empathy, spread knowledge about palliative care and about the importance of care for palliative patients. It is recommended to increase the number of educational activities in small groups, in the local language, adaptable and understandable to all health professionals.