Background: Premenstrual syndrome (PMS) is a disorder affecting large number of population in terms of their physical and psychological well-being. A large number of college drop outs are because of PMS. Aims and Objectives: The objective of this study was to assess the prevalence of presence of different symptoms of PMS and premenstrual dysphoric disorder (PMDD) among medical college girls and its effect on their social and academic life. Materials and Methods: This study was conducted in a medical college in 1

No abstract

The consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) /Coronavirus disease 2019 (COVID-19) on mothers and neonates are uncertain due to the lack of robust evidence from various available studies. Furthermore, conflicting data exist regarding the vertical transmission of coronavirus. Therefore, a hospital-based study was conducted to evaluate the effect of COVID-19 on maternal and perinatal outcomes of COVID-19 infected pregnant women. MethodologyA hospital-based retrospective observational study was conducted between July-December 2020 in Rajarshi Dashrath Autonomous State Medical College, Ayodhya, Uttar Pradesh, a designated level-2 COVID-19 Hospital. A total of 37 confirmed COVID-19 positive pregnant women (mean age 27.5 ± 05 years) of more than 28 weeks of gestation were included in this study to evaluate the effect of COVID-19 on maternal and perinatal outcomes. Maternal symptoms related to COVID-19, comorbidities, intensive care unit (ICU) admissions, intrauterine growth retardation (IUGR), leaking per vagina, mode of delivery, preterm deliveries, and maternal deaths were recorded. Birth weight of newborns, neonatal intensive care unit (NICU) admissions, neonatal illness, neonatal deaths, and COVID-19 testing reports were recorded. ResultOut of 37 COVID-19 positive pregnant women, 27 (72.9%) women were asymptomatic, nine (24.4%) women were having mild disease, and one (2.7%) developed severe disease requiring ICU admission. No maternal deaths were observed. Twenty-six (70.3%) women were delivered by caesarean section, 11 (29.7%) women by normal vaginal delivery, four (10.8%) were of leaking per vagina. Among newborns, five (13.5%) were preterm, one (2.7%) newborn require NICU admission, two (5.4%) were tested COVID-19 positive on the 5th day of life but were asymptomatic, and four (10.8%) newborns developed a fever but were COVID-19 negative. One case (2.7%) was of stillbirth. No neonatal deaths were observed. ConclusionThe present study did not reveal any direct evidence for vertical transmission of SARS-CoV-2 virus through the placenta and during vaginal delivery, but the possibility of mother-to-child infection cannot be completely ignored. SARS-CoV-2 infection during late pregnancy may have a maternal and neonatal impact. COVID-19 infections in late pregnancy might lead to an increased incidence of caesarean deliveries as observed in the present study. This study reveals that most of the COVID-19 positive pregnant women remained asymptomatic or had mild infections. Hence, efforts to limit exposure to COVID-19 of pregnant women should be strengthened for saving mother and child.

Background: Obesity is the leading public health crisis of our time. A chronic imbalance between energy intake and energy expenditure will eventually lead to obesity. Several micronutrients are found to be involved in the development of obesity. Magnesium is found to have some role in the development of obesity. Aims and Objective: Objective of this study was to evaluate the correlation of serum magnesium with different parameters of obesity such as body weight, basal metabolic rate, waist circumference (WC), and waist-hip ratio on the basis of the hypothesis that subjects with hypomagnesemia are more prone to develop obesity. Materials and Methods: This is a population-based cross-sectional study. A total of 130 apparently healthy adults of age between 25 and 65 years, were recruited with prior ethical approval and written informed consent. Results: Serum magnesium was found to have significant negative correlation with body weight (r = −0.30, P = 0.003) and WC (r = −0.21, P = 0.03). Correlation with rest of the parameters was not significant. Conclusion: On the basis of results it is concluded that hypomagnesemia can be proved to be one of the important predictors of obesity.

Myxoinflammatory fibroblastic sarcoma (MIFS) is a rare soft tissue sarcoma which was initially observed in acral sites and characterised by spindle cells, pleomorphic bizarre cells and distinctive large Reed-Sternberg-like cells admixed with an intense inflammatory cell infiltrates. MIFS manifests as a slow growing often superficial lesion which can be mistaken as infectious or chronic inflammatory process or benign tumours such as nodular fasciitis, giant cell tumour of tendon sheath or synovial pseudocyst. We report a rare presentation of a MIFS in a 38-year-old man with extensive local spread from subcutaneous tissue to the ankle joint and bones as well as multiple synchronous metastases to lung, sixth rib and vertebra. Our case is peculiar for its aggressive clinical behaviour with short duration, fast growth and extensive metastases, a feature infrequent in MIFS.