Edible blueberry species are well recognized for their potential health benefits. Ericaceae fruits including the North American highbush blueberry (Vaccinium corymbosum L.) and five less common edible blueberry relatives from the New World tropics, Anthopterus wardii Ball, Cavendishia grandifolia Hoerld, Macleania coccoloboides A. C. Sm., Sphyrospermum buxifolium Poepp. & Endl., and Sphyrospermum cordifolium Benth, were investigated for their antioxidant properties and phenolic profiles. The Neotropical berries C. grandifolia and A. wardii exhibited significantly higher DPPH• and ABTS•+ scavenging and iron chelation activities than V. corymbosum. Total phenolic content and HPLC-PDA compositional fingerprint analyses were also carried out. Significant correlations were observed among total phenolic contents, DPPH• and ABTS•+ scavenging, and iron chelation activities. Using HPLC-PDA, the phenolic constituents in the berries were identified as chlorogenic acid, p-coumaric acid, hyperoside, quercetin-3-O-glucoside, isoorientin, isovitexin, orientin and vitexin. Principal components analysis reduced the dimensions of antioxidant and total phenolic data to two components, which accounted for 95% of total variation among the six fruits. Each fruit species formed its own cluster, and therefore the antioxidant profile of each species was shown to be distinct.
Cigarette smoking is a major health concern, especially among college students. Research suggests a number of individual difference variables may be useful for identifying people at risk of becoming smokers and their likelihood of successfully quitting. The current study focuses on individual differences relating to Behavioral Inhibition System sensitivity (BIS) and the fun seeking, reward responsiveness, and drive aspects of Behavioral Approach System sensitivity (BAS). The former relates to mitigation of potential threat, whereas the latter three relate to different motivations for approach. Noting that existing literature suggests the considerations influencing whether a person experiments with cigarettes differ from those influencing who becomes a habitual smoker which in turn differ from those influencing whether a person quits smoking, we hypothesized that never smokers, experimenters, smokers, and former smokers would differ from each other on BIS, fun seeking, reward responsiveness, and drive in predictable ways. Moreover, we predicted these groups would differ from each other in terms of member profiles across these four variables. We assessed these predictions in a sample of college students from geographically diverse institutions within the United States (N = 1840). Results indicate the profile for never smokers was characterized by high BIS and low fun seeking, that of experimenters by moderately high BIS, high fun seeking, and moderate reward responsiveness, and of former smokers by moderate BIS, high fun seeking, high reward responsiveness, and high drive. Contrary to expectations, current smokers were low on all four of these characteristics.
Myrciaria cauliflora (jaboticaba) is an edible fruit common in Brazil that has been used for treating respiratory diseases, including chronic tonsillitis and asthma. This study explores the distribution of an anti-inflammatory depside, jaboticabin, in different parts of the jaboticaba plant as well as major polyphenols from the wood of jaboticaba, some with biological activity similar to jaboticabin. The peel of the fruit was found to be the major source of jaboticabin. This is the first phytochemical study of the wood of M. cauliflora. The antioxidant-activity-guided fractionation strategy successfully identified 3,3′-dimethylellagic acid-4-O-sulfate from jaboticaba wood. This ellagic acid derivative, in a manner similar to jaboticabin, showed antiradical activity and inhibited the production of the chemokine interleukin-8 after treating the human small airway epithelial cells with cigarette smoke extract. The human intestinal Caco-2 cell studies demonstrated the jaboticabin transport in vitro. The polyphenols, jaboticabin and 3,3′-dimethyellagic acid-4-O-sulfate, from jaboticaba were both found to exhibit anti-inflammatory activities, thus suggesting the potential use of these compounds or even the fruits themselves for chronic obstructive pulmonary disease.
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