A 1% crosslinked divinylbenzene-styrene copolymer, incorporating benzyl acrylate groups, reacted in normal Diels–Alder reactions with E-1-phenyl-1,3-butadiene or methyl E-2,4-pentadienoate to give their respective polymer-bound benzyl cyclohexenecarboxylates. Polymer-bound benzyl propiolate and polymer-bound benzyl phenylpropiolate reacted with benzonitrile oxide in a typical 1,3-dipolar addition reaction to give their respective polymer-bound isoxazoles. Cleavage of the polymer-bound Diels–Alder adducts and the polymer-bound 1,3-dipolar addition adduct derived from polymer-bound benzyl propiolate gave mixtures of ortho and meta regiomers similar to those produced in analogous reactions in solution. Cleavage of the polymer-bound 1,3-dipolar addition adduct, derived from polymer-bound benzyl phenylpropiolate, followed by esterification, gave a solitary adduct, 4-carbomethoxy-3,5-diphenylisoxazole, but an analogous solution 1,3-dipolar addition yielded a 1:1 ratio of the two possible regiomers.

The uracil analog, 4fluoro.2.pyridone was synthesized by ether cleavage of 4-fluoro-2-methoxypyridine with trimethylsilyl iodide. Improved procedures for the preparatiore of 2-methoxypyridine lV-oxide hydrochloride and 2-methoxy4.nitropyridine y'foxide are described. [6] have been described, the desired ,lfluoro-2-pyridone (l) was unknown. Since it was well documented that 4.fluoropyridine was an unstable elusive compound [7,18], there was concern that the related 4-fluoro-2-pyridone (l) would be difficult to prepare. Although some care must be exercised in the isolation of I (see Experimental), compound I was prepared using sone of the methods related to those of Nesnow and Heidelberger [4]

A 1% crosslinked divinylbenzene–styrene copolymer, incorporating benzyl alcohol groups, was used to monoblock the symmetrical diacid chlorides, ClOC(CH2)nCOCl (where n = 4 and 8). Further reaction of the polymer-bound monoester monoacid chloride with phenylmanganese iodide or butylmanganese iodide gave their respective polymer-bound tertiary hydroxyesters. Subsequent base cleavage and esterification yielded methyl 6-hydroxy-6, 6-diphenylhexanoate, methyl 10-hydroxy-10,10-diphenyldecanoate, methyl 6-butyl-6-hydroxydecanoate, and methyl 10-butyl-10-hydroxytetradecanoate and some recovered dimethyl alkanoates. The reactions of some polymer-bound monoester monoacid chlorides with phenylcadmium chloride were also studied.

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Reaktion der aus den Komponenten (I) und (II) erhältlichen polymeren Spezies (III) mit den Dienen (IV) gibt die polymergebundenen Diels‐Alder‐Addukte (V), deren Spaltung und nachfolgende Veresterung Gemische der Isomeren (VIa)+(VIIa) bzw. (VIb)+(VIIb) (jeweils cis‐trans‐Gemisch) liefern.