Background:Central and Peripheral giant cell granulomas of jaws are uncommon, benign, reactive disorders that are characterized by the presence of numerous multinucleated giant cells and mononuclear cells within a stroma. The origin of the multinucleated giant cells is controversial; probably originating from fusion of histiocytes, endothelial cells and fibroblasts.Objective:To assess the expression of CD34 and CD68 in central and peripheral giant cell granulomas to understand the origin of these multinucleated giant cells.Materials and Methods:Twenty cases of Central and Peripheral giant cell granulomas were evaluated immunohistochemically for CD34 and CD68 proteins expression.Results:Immunopositivity for CD34 was seen only in cytoplasm of endothelial cells of blood vessels; whereas, consistent cytoplasmic immunopositivity for CD68 was seen in few stromal cells. Statistical significance was seen in mean number of multinucleated giant cells, mean number of nuclei in multinucleated giant cells, CD68 expression and ratio of macrophages to multinucleated giant cells among two lesions.Conclusion:Although the central giant cell granulomas share some clinical and histopathological similarities with peripheral giant cell granulomas, differences in mean number of nuclei in multinucleated giant cells and CD68 immunoreactivity may underlie the distinct clinical behavior.

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Aims: To record selected dental morphological features among students of our medical campus, to correlate type of dental features in males and females and to maintain records of these dental features among the study population as database for personal identification. Methodology: The present cross-sectional survey was carried out among students of Bharati Vidyapeeth Medical Campus, Sangli aged between 18-25 years. The detailed clinical examination was done to record various dental morphological features. Descriptive statistics were employed. Results: Overall, 720 students from the medical, dental and nursing colleges of our medical campus took part in the survey, consisting of 309 (42.91%) males and 411 (57.08%) females. The selected dental features were observed in 13.7% (n=97) of subjects. The most frequent features detected were talon’s cusp & cusp of Carabelli and the least being parastyle, protostylid and fusion. Cusp of Carabelli showed frequent bilateral presence than unilateral. Conclusion: The study findings stipulate an evolutionary reduction in the size of human dentition. The study highlighted the necessity for understanding the forensic value of these dental morphological features and maintenance of dental records as an adjuvant in person identification.

In a medicolegal investigation, a forensic pathologist, sometimes known as a forensic dentist, works hand in hand with a police officer to determine an individual's identification as a source of information. The blood group might be essential in establishing the victim's identification and the culprits who committed the crime in medico-legal investigations. Because dental tissues are hard of all human tissues and may be conserved for a long time even after death, they are significant for forensic purposes. The main goal of this study was to use the Adsorption-Elution method to detect blood group and Rhesus factor from soft and hard tissue of the tooth as biological evidence and also determine the ABO blood grouping from patients and cadavers in forensic investigation. The results showed, that there was a strong positive matching of the blood grouping with the coagulation of the tooth specimen.

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